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Safety and efficacy evaluation of intracerebroventricular human neural stem cell transplantation in SOD1 mice as a novel approach for ALS.

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Title: Safety and efficacy evaluation of intracerebroventricular human neural stem cell transplantation in SOD1 mice as a novel approach for ALS.
Authors: Lombardi I; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy., Ferrero C; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy.; University School for Advanced Studies IUSS Pavia, Pavia, Italy., Vulcano E; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy., Rasà DM; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy.; University School for Advanced Studies IUSS Pavia, Pavia, Italy., Gelati M; Production Unit of Advanced Therapies (UPTA), Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy., Pastor D; Sport Research Centre, Miguel Hernández University, Avinguda de la Universitat d'Elx, Elche, Spain., Carletti RM; Production Unit of Advanced Therapies (UPTA), Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy., de la Morena S; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy., Profico DC; Production Unit of Advanced Therapies (UPTA), Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy., Longobardi S; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy., Lazzarino E; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy., Perciballi E; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.; Production Unit of Advanced Therapies (UPTA), Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy., Rosati JD; Cellular Reprogramming Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.; UniCamillus - Saint Camillus International University of Health Sciences, Rome, Italy., Martinez S; Instituto de Neurociencias de Alicante (UMH-CSIC), Universidad Miguel Hernandez, San Juan, Alicante, Spain., Vercelli A; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy., Vescovi AL; Faculty of Medicine, Link Campus University, Rome, Italy.; Abu Dhabi Stem Cell Centre, Abu Dhabi, United Arab Emirates., Boido M; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy. marina.boido@unito.it.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy. marina.boido@unito.it., Ferrari D; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy. daniela.ferrari@unimib.it.
Source: Journal of translational medicine [J Transl Med] 2025 May 09; Vol. 23 (1), pp. 529. Date of Electronic Publication: 2025 May 09.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety and efficacy evaluation of intracerebroventricular human neural stem cell transplantation in SOD1 mice as a novel approach for ALS.
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  Data: <searchLink fieldCode="AU" term="%22Lombardi+I%22">Lombardi I</searchLink>; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrero+C%22">Ferrero C</searchLink>; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy.; University School for Advanced Studies IUSS Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Vulcano+E%22">Vulcano E</searchLink>; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rasà+DM%22">Rasà DM</searchLink>; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy.; University School for Advanced Studies IUSS Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Gelati+M%22">Gelati M</searchLink>; Production Unit of Advanced Therapies (UPTA), Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.<br /><searchLink fieldCode="AU" term="%22Pastor+D%22">Pastor D</searchLink>; Sport Research Centre, Miguel Hernández University, Avinguda de la Universitat d'Elx, Elche, Spain.<br /><searchLink fieldCode="AU" term="%22Carletti+RM%22">Carletti RM</searchLink>; Production Unit of Advanced Therapies (UPTA), Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.<br /><searchLink fieldCode="AU" term="%22de+la+Morena+S%22">de la Morena S</searchLink>; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Profico+DC%22">Profico DC</searchLink>; Production Unit of Advanced Therapies (UPTA), Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.<br /><searchLink fieldCode="AU" term="%22Longobardi+S%22">Longobardi S</searchLink>; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lazzarino+E%22">Lazzarino E</searchLink>; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Perciballi+E%22">Perciballi E</searchLink>; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.; Production Unit of Advanced Therapies (UPTA), Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.<br /><searchLink fieldCode="AU" term="%22Rosati+JD%22">Rosati JD</searchLink>; Cellular Reprogramming Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.; UniCamillus - Saint Camillus International University of Health Sciences, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Martinez+S%22">Martinez S</searchLink>; Instituto de Neurociencias de Alicante (UMH-CSIC), Universidad Miguel Hernandez, San Juan, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Vercelli+A%22">Vercelli A</searchLink>; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Vescovi+AL%22">Vescovi AL</searchLink>; Faculty of Medicine, Link Campus University, Rome, Italy.; Abu Dhabi Stem Cell Centre, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Boido+M%22">Boido M</searchLink>; Neuroscience Institute Cavalieri Ottolenghi (N.I.C.O.), University of Turin, Turin, Italy. marina.boido@unito.it.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy. marina.boido@unito.it.<br /><searchLink fieldCode="AU" term="%22Ferrari+D%22">Ferrari D</searchLink>; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy. daniela.ferrari@unimib.it.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2025 May 09; Vol. 23 (1), pp. 529. <i>Date of Electronic Publication: </i>2025 May 09.
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