Spatial transcriptomics reveals human cortical layer and area specification.
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| Title: | Spatial transcriptomics reveals human cortical layer and area specification. |
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| Authors: | Qian X; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. qianxuyu@gmail.com.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. qianxuyu@gmail.com., Coleman K; Statistical Center for Single-Cell and Spatial Genomics, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Jiang S; Statistical Center for Single-Cell and Spatial Genomics, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kriz AJ; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Marciano JH; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Luo C; Statistical Center for Single-Cell and Spatial Genomics, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Cai C; Research Computing, Department of Information Technology, Boston Children's Hospital, Boston, MA, USA., Manam MD; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Caglayan E; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Lai A; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Exposito-Alonso D; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Otani A; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Ghosh U; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Shao DD; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Boston Children's Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Andersen RE; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Neil JE; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Johnson R; University of Maryland Brain and Tissue Bank, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA., LeFevre A; University of Maryland Brain and Tissue Bank, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA., Hecht JL; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Micali N; Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA., Sestan N; Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, CT, USA.; Wu Tsai Institute, Yale University, New Haven, CT, USA., Rakic P; Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA., Miller MB; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Neuropathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA., Sun L; Research Computing, Department of Information Technology, Boston Children's Hospital, Boston, MA, USA., Stringer C; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA., Li M; Statistical Center for Single-Cell and Spatial Genomics, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mingyao@pennmedicine.upenn.edu.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mingyao@pennmedicine.upenn.edu., Walsh CA; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. christopher.walsh@childrens.harvard.edu.; Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. christopher.walsh@childrens.harvard.edu.; Department of Neurology, Boston Children's Hospital, Boston, MA, USA. christopher.walsh@childrens.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. christopher.walsh@childrens.harvard.edu.; Departments of Pediatrics and Neurology, Harvard Medical School, Boston, MA, USA. christopher.walsh@childrens.harvard.edu. |
| Source: | Nature [Nature] 2025 Aug; Vol. 644 (8075), pp. 153-163. Date of Electronic Publication: 2025 May 14. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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