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Astrocyte-derived CCL5-mediated CCR5+ neutrophil infiltration drives depression pathogenesis.

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Title: Astrocyte-derived CCL5-mediated CCR5+ neutrophil infiltration drives depression pathogenesis.
Authors: Yao H; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China., Jiang SY; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China., Jiao YY; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China., Zhou ZY; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China., Zhu Z; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China., Wang C; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China., Zhang KZ; Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China., Ma TF; Institute for Stem Cell and Neural Regeneration and Key Laboratory of Cardiovascular & Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University, Nanjing 211166, P.R. China., Hu G; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China., Du RH; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China., Lu M; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China.; Changzhou Second People's Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou 213000, P.R. China.
Source: Science advances [Sci Adv] 2025 May 23; Vol. 11 (21), pp. eadt6632. Date of Electronic Publication: 2025 May 21.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Astrocyte-derived CCL5-mediated CCR5<superscript>+</superscript> neutrophil infiltration drives depression pathogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Yao+H%22">Yao H</searchLink>; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China.<br /><searchLink fieldCode="AU" term="%22Jiang+SY%22">Jiang SY</searchLink>; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China.<br /><searchLink fieldCode="AU" term="%22Jiao+YY%22">Jiao YY</searchLink>; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhou+ZY%22">Zhou ZY</searchLink>; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhu+Z%22">Zhu Z</searchLink>; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+KZ%22">Zhang KZ</searchLink>; Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China.<br /><searchLink fieldCode="AU" term="%22Ma+TF%22">Ma TF</searchLink>; Institute for Stem Cell and Neural Regeneration and Key Laboratory of Cardiovascular & Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University, Nanjing 211166, P.R. China.<br /><searchLink fieldCode="AU" term="%22Hu+G%22">Hu G</searchLink>; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China.<br /><searchLink fieldCode="AU" term="%22Du+RH%22">Du RH</searchLink>; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China.<br /><searchLink fieldCode="AU" term="%22Lu+M%22">Lu M</searchLink>; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing 211166, P.R. China.; Changzhou Second People's Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou 213000, P.R. China.
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  Data: <searchLink fieldCode="JN" term="%22101653440%22">Science advances</searchLink> [Sci Adv] 2025 May 23; Vol. 11 (21), pp. eadt6632. <i>Date of Electronic Publication: </i>2025 May 21.
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              Text: 2025 May 23
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