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Prediction Pathway for Severe Asthma Exacerbations: A Bayesian Network Analysis.

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Title: Prediction Pathway for Severe Asthma Exacerbations: A Bayesian Network Analysis.
Authors: Yadav CP; Saw Swee Hock School of Public Health, National University of Singapore, Ann Arbor, MI., Chakraborty A; University of Michigan, Ann Arbor, MI., Price DB; Optimum Patient Care Global, Cambridge, England; Observational and Pragmatic Research Institute, Singapore; Division of Applied Health Sciences, Centre of Academic Primary Care, University of Aberdeen, Aberdeen, Scotland., Lim LHM; Saw Swee Hock School of Public Health, National University of Singapore, Ann Arbor, MI., Juang YR; Saw Swee Hock School of Public Health, National University of Singapore, Ann Arbor, MI., Beasley R; Medical Research Institute of New Zealand, Wellington, New Zealand., Sadatsafavi M; Respiratory Evaluation Sciences Program, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada., Janson C; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Siyue MK; Duke-NUS Medical School, Singapore; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore., Wang E; Division of Allergy and Clinical Immunology, Department of Medicine, National Jewish Health, Denver, CO; Division of Allergy and Clinical Immunology, Department of Medicine, University of Colorado School of Medicine, Aurora, CO., Wechsler ME; NJH Cohen Family Asthma Institute, Department of Medicine, National Jewish Health, Denver, CO., Jackson DJ; UK Severe Asthma Network and National Registry, Guy's and St Thomas' NHS Trust, London, England; School of Immunology and Microbial Sciences, King's College London, London, England., Busby J; Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland., Heaney LG; Wellcome-Wolfson Centre for Experimental Medicine, Queen's University Belfast, Belfast, Northern Ireland., Pfeffer PE; Department of Respiratory Medicine, Barts Health NHS Trust, London, England; Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, England., Mahboub B; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; Rashid Hospital, Dubai Health Authority, Dubai, United Arab Emirates., Perng DW; Division of Clinical Respiratory Physiology, Chest Department, Taipei Veterans General Hospital, Taipei City, Taiwan; COPD Assembly of the Asian Pacific Society of Respirology, Tokyo, Japan., Cosio BG; Son Espases University Hospital-IdISBa-CIBERES, Mallorca, Spain., Perez-de-Llano L; Pneumology Service, Lucus Augusti University Hospital, EOXI Lugo-Monforte-Cervo, Lugo, Spain; Biodiscovery Research Group, Health Research Institute of Santiago de Compostela, Santiago de Compostela, Spain., Al-Lehebi R; Department of Pulmonology, King Fahad Medical City, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Larenas-Linnemann D; Centro de Excelencia en Asma y Alergia, Hospital Médica Sur, Mexico City, Mexico., Al-Ahmad MS; Microbiology Department, College of Medicine, Kuwait University, and Al-Rashed Allergy Center, Ministry of Health, Kuwait City, Kuwait., Rhee CK; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, and College of Medicine, Catholic University of Korea, Seoul, South Korea., Iwanaga T; Sleep Medicine Center, Kindai University Hospital, Osakasayama, Japan., Heffler E; Personalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center, IRCCS, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Canonica GW; Personalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center, IRCCS, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Costello RW; Clinical Research Centre, Beaumont Hospital, and Department of Respiratory Medicine, RCSI, Dublin, Ireland., Papadopoulos NG; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, England; Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece., Papaioannou AI; 2nd Respiratory Medicine Department, National and Kapodistrian University of Athens Medical School, and Attikon University Hospital, Athens, Greece., Porsbjerg CM; Respiratory Research Unit, Bispebjerg University Hospital, Copenhagen, Denmark; Allergy, Asthma and Clinical Immunology Service, Alfred Health, Melbourne, Australia., Torres-Duque CA; CINEUMO, Respiratory Research Center, Fundación Neumológica Colombiana, Bogotá, Colombia., Christoff GC; Medical University-Sofia, Faculty of Public Health, Sofia, Bulgaria., Popov TA; Clinic of Occupational Diseases, University Hospital 'Sv. Ivan Rilski,' Sofia, Bulgaria., Hew M; Allergy, Asthma and Clinical Immunology Service, Alfred Health, Melbourne, Australia; Public Health and Preventive Medicine, Monash University, Melbourne, Australia., Peters MJ; Department of Thoracic Medicine, Concord Hospital, Sydney, Australia., Gibson PG; Australian Severe Asthma Network, Priority Research Centre for Healthy Lungs, University of Newcastle, Newcastle, Australia; Hunter Medical Research Institute, Department of Respiratory and Sleep Medicine, John Hunter Hospital, New Lambton Heights, Australia., Máspero J; Clinical Research for Allergy and Respiratory Medicine, CIDEA Foundation, Buenos Aires, Argentina; University Career of Specialists in Allergy and Clinical Immunology, Buenos Aires University School of Medicine, Buenos Aires, Argentina., Bergeron C; Centre for Lung Health, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada., Cerda S; Medical Specialties Unit, Secretary of National Defense, Mexico City, Mexico., Contreras EA; Mexican Council of Clinical Immunology and Allergy, Mexico City Office, Mexico City, Mexico; Department of Allergy and Clinical Immunology, Lic. Adolfo López Mateos Regional Hospital of the Institute of Security and Social Services for State Workers (ISSSTE), Mexico City, Mexico., Chen W; Saw Swee Hock School of Public Health, National University of Singapore, Ann Arbor, MI. Electronic address: wenjiach@nus.edu.sg.
Source: Chest [Chest] 2025 Aug; Vol. 168 (2), pp. 301-316. Date of Electronic Publication: 2025 May 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0231335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-3543 (Electronic) Linking ISSN: 00123692 NLM ISO Abbreviation: Chest Subsets: MEDLINE
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Medical Research Institute of New Zealand, Wellington, New Zealand.<br /><searchLink fieldCode="AU" term="%22Sadatsafavi+M%22">Sadatsafavi M</searchLink>; Respiratory Evaluation Sciences Program, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Janson+C%22">Janson C</searchLink>; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Siyue+MK%22">Siyue MK</searchLink>; Duke-NUS Medical School, Singapore; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+E%22">Wang E</searchLink>; Division of Allergy and Clinical Immunology, Department of Medicine, National Jewish Health, Denver, CO; Division of Allergy and Clinical Immunology, Department of Medicine, University of Colorado School of Medicine, Aurora, CO.<br /><searchLink fieldCode="AU" term="%22Wechsler+ME%22">Wechsler ME</searchLink>; 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Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Canonica+GW%22">Canonica GW</searchLink>; Personalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center, IRCCS, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Costello+RW%22">Costello RW</searchLink>; Clinical Research Centre, Beaumont Hospital, and Department of Respiratory Medicine, RCSI, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Papadopoulos+NG%22">Papadopoulos NG</searchLink>; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, England; Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Papaioannou+AI%22">Papaioannou AI</searchLink>; 2nd Respiratory Medicine Department, National and Kapodistrian University of Athens Medical School, and Attikon University Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Porsbjerg+CM%22">Porsbjerg CM</searchLink>; 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