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CSF proteomics of semorinemab Alzheimer's disease trials identifies cell-type specific signatures.

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Title: CSF proteomics of semorinemab Alzheimer's disease trials identifies cell-type specific signatures.
Authors: Abdel-Haleem AM; Roche Informatics, F. Hoffmann-La Roche Ltd., Mississauga, ON L5N 5M8, Canada., Casavant E; Department of Translational Medicine, Genentech, Inc., South San Francisco, CA 94080, USA., Toth B; Department of Data and Statistical Sciences, Genentech, Inc., South San Francisco, CA 94080, USA., Teng E; Department of Early Clinical Development-OMNI, Genentech, Inc., South San Francisco, CA 94080, USA., Monteiro C; Department of Early Clinical Development-OMNI, Genentech, Inc., South San Francisco, CA 94080, USA., Pandya NJ; Human Pathobiology & OMNI Reverse Translation, Genentech, Inc., South San Francisco, CA 94080, USA., Glock C; Department of Neuroscience, Genentech, Inc., South San Francisco, CA 94080, USA.; gRED Computational Sciences, Genentech, Inc., South San Francisco, CA 94080, USA., Hoogenraad CC; Department of Neuroscience, Genentech, Inc., South San Francisco, CA 94080, USA., Friedman BA; gRED Computational Sciences, Genentech, Inc., South San Francisco, CA 94080, USA., Yeh FL; Department of Translational Medicine, Genentech, Inc., South San Francisco, CA 94080, USA., Anania VG; Department of Translational Medicine, Genentech, Inc., South San Francisco, CA 94080, USA., Novikova G; gRED Computational Sciences, Genentech, Inc., South San Francisco, CA 94080, USA.
Source: Brain : a journal of neurology [Brain] 2026 Jan 08; Vol. 149 (1), pp. 150-162.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CSF proteomics of semorinemab Alzheimer's disease trials identifies cell-type specific signatures.
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  Data: <searchLink fieldCode="AU" term="%22Abdel-Haleem+AM%22">Abdel-Haleem AM</searchLink>; Roche Informatics, F. Hoffmann-La Roche Ltd., Mississauga, ON L5N 5M8, Canada.<br /><searchLink fieldCode="AU" term="%22Casavant+E%22">Casavant E</searchLink>; Department of Translational Medicine, Genentech, Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Toth+B%22">Toth B</searchLink>; Department of Data and Statistical Sciences, Genentech, Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Teng+E%22">Teng E</searchLink>; Department of Early Clinical Development-OMNI, Genentech, Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Monteiro+C%22">Monteiro C</searchLink>; Department of Early Clinical Development-OMNI, Genentech, Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Pandya+NJ%22">Pandya NJ</searchLink>; Human Pathobiology & OMNI Reverse Translation, Genentech, Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Glock+C%22">Glock C</searchLink>; Department of Neuroscience, Genentech, Inc., South San Francisco, CA 94080, USA.; gRED Computational Sciences, Genentech, Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Hoogenraad+CC%22">Hoogenraad CC</searchLink>; Department of Neuroscience, Genentech, Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Friedman+BA%22">Friedman BA</searchLink>; gRED Computational Sciences, Genentech, Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Yeh+FL%22">Yeh FL</searchLink>; Department of Translational Medicine, Genentech, Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Anania+VG%22">Anania VG</searchLink>; Department of Translational Medicine, Genentech, Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Novikova+G%22">Novikova G</searchLink>; gRED Computational Sciences, Genentech, Inc., South San Francisco, CA 94080, USA.
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  Data: <searchLink fieldCode="JN" term="%220372537%22">Brain : a journal of neurology</searchLink> [Brain] 2026 Jan 08; Vol. 149 (1), pp. 150-162.
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  Data: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0372537 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2156 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200068950%22">00068950 </searchLink><i>NLM ISO Abbreviation: </i>Brain <i>Subsets: </i>MEDLINE
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        Value: 10.1093/brain/awaf200
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        Text: English
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            – D: 08
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              Text: 2026 Jan 08
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