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Neurogenin 2-induced central neurons generated from NPC patient-derived iPSC display attenuated neurite outgrowth while accumulating cholesterol.

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Title: Neurogenin 2-induced central neurons generated from NPC patient-derived iPSC display attenuated neurite outgrowth while accumulating cholesterol.
Authors: Igarashi M; Advanced Clinical Research Center, Southern TOHOKU Research Institute for Neuroscience, 255 Furusawa-tsuko, Asao-ku, Kawasaki 215-0026, Japan., Miyajima T; Advanced Clinical Research Center, Southern TOHOKU Research Institute for Neuroscience, 255 Furusawa-tsuko, Asao-ku, Kawasaki 215-0026, Japan., Wu C; Advanced Clinical Research Center, Southern TOHOKU Research Institute for Neuroscience, 255 Furusawa-tsuko, Asao-ku, Kawasaki 215-0026, Japan., Iwamoto T; Advanced Clinical Research Center, Southern TOHOKU Research Institute for Neuroscience, 255 Furusawa-tsuko, Asao-ku, Kawasaki 215-0026, Japan; The Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minato-ku, Tokyo 105-8461, Japan., Eto Y; Advanced Clinical Research Center, Southern TOHOKU Research Institute for Neuroscience, 255 Furusawa-tsuko, Asao-ku, Kawasaki 215-0026, Japan; The Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minato-ku, Tokyo 105-8461, Japan. Electronic address: yosh@sepia.ocn.ne.jp.
Source: Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2025 Aug; Vol. 1870 (6), pp. 159639. Date of Electronic Publication: 2025 May 26.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731727 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2618 (Electronic) Linking ISSN: 13881981 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Biol Lipids Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Neurogenin 2-induced central neurons generated from NPC patient-derived iPSC display attenuated neurite outgrowth while accumulating cholesterol.
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  Data: <searchLink fieldCode="AU" term="%22Igarashi+M%22">Igarashi M</searchLink>; Advanced Clinical Research Center, Southern TOHOKU Research Institute for Neuroscience, 255 Furusawa-tsuko, Asao-ku, Kawasaki 215-0026, Japan.<br /><searchLink fieldCode="AU" term="%22Miyajima+T%22">Miyajima T</searchLink>; Advanced Clinical Research Center, Southern TOHOKU Research Institute for Neuroscience, 255 Furusawa-tsuko, Asao-ku, Kawasaki 215-0026, Japan.<br /><searchLink fieldCode="AU" term="%22Wu+C%22">Wu C</searchLink>; Advanced Clinical Research Center, Southern TOHOKU Research Institute for Neuroscience, 255 Furusawa-tsuko, Asao-ku, Kawasaki 215-0026, Japan.<br /><searchLink fieldCode="AU" term="%22Iwamoto+T%22">Iwamoto T</searchLink>; Advanced Clinical Research Center, Southern TOHOKU Research Institute for Neuroscience, 255 Furusawa-tsuko, Asao-ku, Kawasaki 215-0026, Japan; The Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minato-ku, Tokyo 105-8461, Japan.<br /><searchLink fieldCode="AU" term="%22Eto+Y%22">Eto Y</searchLink>; Advanced Clinical Research Center, Southern TOHOKU Research Institute for Neuroscience, 255 Furusawa-tsuko, Asao-ku, Kawasaki 215-0026, Japan; The Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minato-ku, Tokyo 105-8461, Japan. Electronic address: yosh@sepia.ocn.ne.jp.
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  Data: <searchLink fieldCode="JN" term="%22101731727%22">Biochimica et biophysica acta. Molecular and cell biology of lipids</searchLink> [Biochim Biophys Acta Mol Cell Biol Lipids] 2025 Aug; Vol. 1870 (6), pp. 159639. <i>Date of Electronic Publication: </i>2025 May 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101731727 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-2618 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213881981%22">13881981 </searchLink><i>NLM ISO Abbreviation: </i>Biochim Biophys Acta Mol Cell Biol Lipids <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bbalip.2025.159639
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        Text: English
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        StartPage: 159639
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      – TitleFull: Neurogenin 2-induced central neurons generated from NPC patient-derived iPSC display attenuated neurite outgrowth while accumulating cholesterol.
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            NameFull: Igarashi M
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              Text: 2025 Aug
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              Y: 2025
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