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Transarterial chemoembolization plus apatinib for unresectable hepatocellular carcinoma: a multicenter, randomized, open-label, phase III trial.

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Title: Transarterial chemoembolization plus apatinib for unresectable hepatocellular carcinoma: a multicenter, randomized, open-label, phase III trial.
Authors: Kan XF; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Liang B; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhang XL; Department of Interventional Radiology, The First College of Clinical Medical Science, Yichang Central People's Hospital, China Three Gorges University, Yichang, Hubei, China., Yu L; Department of Interventional Radiology, Guangxi Zhuang Autonomous Region People's Hospital, Nanning, China., Luo YC; Department of Catheter Intervention, First Affiliated Hospital of Guangxi, University of Traditional Chinese Medicine, Nanning, China., Zhou S; Department of Interventional Radiology, The Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, China.; Department of Interventional Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China., Liu RB; Department of Interventional Radiology, Harbin Medical University Cancer Hospital, Harbin, China., Xu GH; Department of Interventional Radiology, School of Medicine, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China., Li HL; Department of Radiology and Intervention, The Affiliated Tumor Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, China., Liao ZY; Department of Abdominal Oncology, West China Medical School, West China Hospital, Sichuan University, Chengdu, China., Xiang H; Department of Interventional Radiology and Vascular Surgery, Hunan Provincial People's Hospital, Changsha, China., Lu W; Department of Interventional Medicine, The Sixth Medical Center of Chinese PLA General Hospital, Beijing, China., Xu LF; Department of Interventional Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China., Ma YL; Department of Interventional Radiology, Guangxi Medical University Cancer Hospital, Guangxi Medical University, Nanning, China., Xia XW; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Qian K; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Dong XJ; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Xiong F; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Song SL; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhao C; Department of Interventional Radiology, Guangxi Medical University Cancer Hospital, Guangxi Medical University, Nanning, China. 710519137@qq.com., Huang M; Department of Minimally Invasive International Therapy, The Third Affiliated Hospital of Kunming University, Tumor Hospital of Yunnan Province, Kunming, Yunnan Province, 650000, China. huangming4328@sina.com., Zheng CS; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. hqzcsxh@sina.com.
Source: BMC medicine [BMC Med] 2025 May 28; Vol. 23 (1), pp. 313. Date of Electronic Publication: 2025 May 28.
Publication Type: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Transarterial chemoembolization plus apatinib for unresectable hepatocellular carcinoma: a multicenter, randomized, open-label, phase III trial.
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  Data: <searchLink fieldCode="AU" term="%22Kan+XF%22">Kan XF</searchLink>; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Liang+B%22">Liang B</searchLink>; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Zhang+XL%22">Zhang XL</searchLink>; Department of Interventional Radiology, The First College of Clinical Medical Science, Yichang Central People's Hospital, China Three Gorges University, Yichang, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Yu+L%22">Yu L</searchLink>; Department of Interventional Radiology, Guangxi Zhuang Autonomous Region People's Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Luo+YC%22">Luo YC</searchLink>; Department of Catheter Intervention, First Affiliated Hospital of Guangxi, University of Traditional Chinese Medicine, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Zhou+S%22">Zhou S</searchLink>; Department of Interventional Radiology, The Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, China.; Department of Interventional Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.<br /><searchLink fieldCode="AU" term="%22Liu+RB%22">Liu RB</searchLink>; Department of Interventional Radiology, Harbin Medical University Cancer Hospital, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Xu+GH%22">Xu GH</searchLink>; Department of Interventional Radiology, School of Medicine, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Li+HL%22">Li HL</searchLink>; Department of Radiology and Intervention, The Affiliated Tumor Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Liao+ZY%22">Liao ZY</searchLink>; Department of Abdominal Oncology, West China Medical School, West China Hospital, Sichuan University, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Xiang+H%22">Xiang H</searchLink>; Department of Interventional Radiology and Vascular Surgery, Hunan Provincial People's Hospital, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Lu+W%22">Lu W</searchLink>; Department of Interventional Medicine, The Sixth Medical Center of Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Xu+LF%22">Xu LF</searchLink>; Department of Interventional Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Ma+YL%22">Ma YL</searchLink>; Department of Interventional Radiology, Guangxi Medical University Cancer Hospital, Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Xia+XW%22">Xia XW</searchLink>; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Qian+K%22">Qian K</searchLink>; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Dong+XJ%22">Dong XJ</searchLink>; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Xiong+F%22">Xiong F</searchLink>; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Song+SL%22">Song SL</searchLink>; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Zhao+C%22">Zhao C</searchLink>; Department of Interventional Radiology, Guangxi Medical University Cancer Hospital, Guangxi Medical University, Nanning, China. 710519137@qq.com.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; Department of Minimally Invasive International Therapy, The Third Affiliated Hospital of Kunming University, Tumor Hospital of Yunnan Province, Kunming, Yunnan Province, 650000, China. huangming4328@sina.com.<br /><searchLink fieldCode="AU" term="%22Zheng+CS%22">Zheng CS</searchLink>; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. hqzcsxh@sina.com.
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  Data: <searchLink fieldCode="JN" term="%22101190723%22">BMC medicine</searchLink> [BMC Med] 2025 May 28; Vol. 23 (1), pp. 313. <i>Date of Electronic Publication: </i>2025 May 28.
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  Data: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190723 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1741-7015 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217417015%22">17417015 </searchLink><i>NLM ISO Abbreviation: </i>BMC Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12916-025-04159-y
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