T-cell and antibody responses in immunocompromised patients with hematologic malignancies indicate strong potential of SARS-CoV-2 mRNA vaccines.

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Bibliographic Details
Title: T-cell and antibody responses in immunocompromised patients with hematologic malignancies indicate strong potential of SARS-CoV-2 mRNA vaccines.
Authors: Pothast CR; Department of Hematology, Leiden UMC, Leiden., Hofsink Q; Department of Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam UMC, Amsterdam., Haggenburg S; Department of Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam UMC, Amsterdam., Dijkland RC; Department of Hematology, Leiden UMC, Leiden., Van de Meent M; Department of Hematology, Leiden UMC, Leiden., Van Dijk K; Department of Hematology, Leiden UMC, Leiden., Bhoekhan MS; Department of Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam UMC, Amsterdam., Haverkate NJE; Amsterdam Institute for Infection and Immunity, Amsterdam UMC, Amsterdam, the Netherlands; Department of Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam., Van Meerloo J; Department of Hematology, Amsterdam UMC location Vrije Universiteit, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam UMC, Amsterdam., Falkenburg JHF; Department of Hematology, Leiden UMC, Leiden., De Groen RAL; Department of Hematology, Leiden UMC, Leiden., Broers AEC; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam., Van Doesum JA; Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen., Van Binnendijk RS; Centre for Immunology of Infectious Diseases and Vaccines, National Institute for Public Health and the Environment, Bilthoven, the Netherlands; Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboudumc, Nijmegen., Den Hartog G; Centre for Immunology of Infectious Diseases and Vaccines, National Institute for Public Health and the Environment, Bilthoven., Lissenberg-Witte BI; Department of Epidemiology and Data Science, Amsterdam UMC location Vrije Universiteit, Amsterdam., Kater AP; Department of Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam UMC, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam UMC, Amsterdam., Smits GP; Centre for Immunology of Infectious Diseases and Vaccines, National Institute for Public Health and the Environment, Bilthoven., Wouters D; Department of Laboratory Medicine, Central Diagnostic Laboratory, Amsterdam UMC, Amsterdam., Van Leeuwen EMM; Amsterdam Institute for Infection and Immunity, Amsterdam UMC, Amsterdam, the Netherlands; Department of Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands; Department of Laboratory Medicine, Laboratory for Specialized Diagnostics and Research, Laboratory Medical Immunology, Amsterdam UMC, Amsterdam., Bontkes HJ; Amsterdam Institute for Infection and Immunity, Amsterdam UMC, Amsterdam, the Netherlands; Department of Laboratory Medicine, Laboratory for Specialized Diagnostics and Research, Laboratory Medical Immunology, Amsterdam UMC, Amsterdam., Kootstra NA; Amsterdam Institute for Infection and Immunity, Amsterdam UMC, Amsterdam, the Netherlands; Department of Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam., Vogels-Nooijen S; Netherlands Comprehensive Cancer Organisation, Utrecht., Van Baarle D; Department of Medical Microbiology and Infection Prevention, University Medical Center Groningen, Groningen., De Vries RD; Department of Viroscience, Erasmus University Medical Center, Rotterdam., Van Meerten T; Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen., Mutsaers PGNJ; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam., Goorhuis A; Department of Infectious Diseases, Amsterdam UMC location University of Amsterdam, Amsterdam., Nijhof IS; Department of Hematology, Amsterdam UMC location Vrije Universiteit, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands; Department of Internal Medicine-Hematology, St. Antonius Hospital, Nieuwegein., Hazenberg MD; Department of Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam UMC, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands; Department of Hematopoiesis, Sanquin Research, Amsterdam., Heemskerk MHM; Department of Hematology, Leiden UMC, Leiden., Rutten CE; Department of Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam. c.e.rutten@amsterdamumc.nl., Study Team CK; Iris Kant, Thecla Graas, Belle Toussaint, Sterre de Jong, Shahan Darwesh, Sandjiv Mahes, Dora Kamminga, Matthijs Koelewijn, Gino Faber, Guus Beaumont, Marije Engel, R. Cheyenne Pierie, Suzanne Janssen, Kazimierz Groen, Judith Burger, Joey Bouhuijs, Paul Baars, Marit van Gils, Edith van Dijkman, Jarom Heijmans, Yara Witte, Rogers Nahui Palomino, Said Omar, Sonja Zweegman, Caya van den Vegt, Ilonka Arends-Halbesma, Emma de Pater, Margriet Dijkstra, Nynke Rots, Esther Siteur-van Rijnstra, Dennis de Rooij, Rogier Sanders, Meliawati Poniman, Wouter Olijhoek, Jacqueline van Rijswijk, Tim Beaumont, Lusia Çetinel, Louis Schellekens, Yvonne den Hartogh, Jacqueline Cloos, Suzanne Weijers, Saïda Tonouh-Aajoud, Selime Avci, Elianne Roelandse-Koop, Willem Dik.
Source: Haematologica [Haematologica] 2025 Nov 01; Vol. 110 (11), pp. 2799-2805. Date of Electronic Publication: 2025 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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