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Clinical, molecular, and radiological predictors of prognosis in newly diagnosed astrocytoma, IDH-mutant, WHO grade 4.

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Title: Clinical, molecular, and radiological predictors of prognosis in newly diagnosed astrocytoma, IDH-mutant, WHO grade 4.
Authors: Lasica AB; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Lan Z; Center for Clinical Investigation, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA., Miller JJ; Pappas Center for Neuro-Oncology, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA., Jiao A; Division of Neuroradiology, Department of Radiology, Brigham and Women's Hospital, Boston, MA, USA., Pan I; Division of Neuroradiology, Department of Radiology, Brigham and Women's Hospital, Boston, MA, USA., Aker L; Division of Neuroradiology, Department of Radiology, Brigham and Women's Hospital, Boston, MA, USA., Prabhakar P; Division of Neuropathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Japo J; Division of Neuropathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Russ A; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Westergaard C; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Aquilanti E; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Chukwueke U; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Gonzalez Castro LN; Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., McFaline Figueroa JR; Department of Neurology, Grossman School of Medicine, New York University, New York, NY, USA.; Brain & Spine Tumor Center, Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA., Lee EQ; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Nayak L; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Beroukhim R; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Batchelor TT; Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA., Cahill DP; Department of Neurosurgery, Mass General Brigham, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA., Nakhate V; Pappas Center for Neuro-Oncology, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Lanman T; Pappas Center for Neuro-Oncology, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Pablo Ospina J; Pappas Center for Neuro-Oncology, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Stec N; Pappas Center for Neuro-Oncology, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Patel RV; Department of Neurosurgery, Mass General Brigham, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA., Meredith DM; Division of Neuropathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA., Bi WL; Department of Neurosurgery, Mass General Brigham, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA., Reardon DA; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Ligon KL; Division of Neuropathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA., Huang RY; Division of Neuroradiology, Department of Radiology, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Harvard University, Boston, MA, USA., Wen PY; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Youssef G; Harvard Medical School, Harvard University, Boston, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Source: Neuro-oncology [Neuro Oncol] 2025 Oct 14; Vol. 27 (9), pp. 2382-2398.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Clinical, molecular, and radiological predictors of prognosis in newly diagnosed astrocytoma, IDH-mutant, WHO grade 4.
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