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Single-cell analyses identify monocyte gene expression profiles that influence HIV-1 reservoir size in acutely treated cohorts.

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Title: Single-cell analyses identify monocyte gene expression profiles that influence HIV-1 reservoir size in acutely treated cohorts.
Authors: Ehrenberg PK; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA., Geretz A; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Volcic M; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany., Izumi T; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; Department of Biology, College of Arts and Sciences, American University, Washington D.C., USA.; District of Columbia Center for AIDS Research, Washington D.C., USA.; Department of Biology, College of Arts and Sciences, Saint Joseph's University, Philadelphia, PA, USA., Yum LK; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Waickman A; Viral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Department of Microbiology and Immunology, State University of New York Upstate Medical University, Syracuse, NY, USA., Shangguan S; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Paquin-Proulx D; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Creegan M; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Bose M; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Machmach K; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., McGraw A; Department of Biology, College of Arts and Sciences, American University, Washington D.C., USA., Narahari A; Department of Biology, College of Arts and Sciences, Saint Joseph's University, Philadelphia, PA, USA., Currier JR; Viral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Sacdalan C; SEARCH Research Foundation, Bangkok, Thailand.; Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Phanuphak N; Institute of HIV Research and Innovation, Bangkok, Thailand., Apps R; NIH Center for Human Immunology, National Institutes of Health, Bethesda, MD, USA., Corley M; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York City, NY, USA.; Department of Medicine, Division of Geriatrics, Gerontology and Palliative Care, The Sam and Rose Stein Institute for Research on Aging and Center for Healthy Aging, University of California, San Diego, CA, USA., Ndhlovu LC; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York City, NY, USA., Slike B; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Krebs SJ; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA., Anonworanich J; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Tovanabutra S; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Robb ML; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Eller MA; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; Vaccine Research Program, Division of AIDS (DAIDS), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Laird GM; Accelevir Diagnostics, Baltimore, MD, USA., Cyktor J; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Daar ES; Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Crowell TA; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Mellors JW; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Vasan S; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Michael NL; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Kirchhoff F; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany., Thomas R; U.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA. rthomas@hivresearch.org.
Source: Nature communications [Nat Commun] 2025 May 29; Vol. 16 (1), pp. 4975. Date of Electronic Publication: 2025 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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