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Application of preclinical absorption, distribution, metabolism, elimination in vitro techniques for the characterization and compound library optimization of novel antibiotic gallium salophen.

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Title: Application of preclinical absorption, distribution, metabolism, elimination in vitro techniques for the characterization and compound library optimization of novel antibiotic gallium salophen.
Authors: Krug SA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland., Frank A; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland., Hwang L; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland., Worth M; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland., Johnson K; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland., Rojas C; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland., Muller L; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland., Michel SLJ; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland., Wilks A; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland., Xue F; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland., Kane MA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland. Electronic address: mkane@rx.umaryland.edu.
Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2025 Jun; Vol. 53 (6), pp. 100080. Date of Electronic Publication: 2025 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Krug+SA%22">Krug SA</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Frank+A%22">Frank A</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Hwang+L%22">Hwang L</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Worth+M%22">Worth M</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Johnson+K%22">Johnson K</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Rojas+C%22">Rojas C</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Muller+L%22">Muller L</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Michel+SLJ%22">Michel SLJ</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Wilks+A%22">Wilks A</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Xue+F%22">Xue F</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Kane+MA%22">Kane MA</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland. Electronic address: mkane@rx.umaryland.edu.
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              Text: 2025 Jun
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