Sonic hedgehog medulloblastomas are dependent on Netrin-1 for survival.
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| Title: | Sonic hedgehog medulloblastomas are dependent on Netrin-1 for survival. |
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| Authors: | Talbot J; Institut Curie, PSL Research University, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France.; Université Paris Sud, Université Paris-Saclay, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France., Fombonne J; Apoptosis, Cancer and Development Laboratory-Equipe labellisée 'La Ligue', LabEx DEVweCAN, Institut Convergence PLAsCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon1, Centre Léon Bérard, Lyon, France., Torrejon J; Institut Curie, PSL Research University, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France.; Université Paris Sud, Université Paris-Saclay, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France., Babcock BR; Cancer Cell Biology Program, Emory University, Atlanta, GA, USA., McSwain LF; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Rama N; Apoptosis, Cancer and Development Laboratory-Equipe labellisée 'La Ligue', LabEx DEVweCAN, Institut Convergence PLAsCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon1, Centre Léon Bérard, Lyon, France., Lospinoso Severini L; Department of Molecular Medicine, University La Sapienza, Rome, Italy., Bonerandi E; Institut Curie, PSL Research University, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France.; Université Paris Sud, Université Paris-Saclay, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France., Marsaud V; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France., Bernardi F; Institut Curie, PSL Research University, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France.; Université Paris Sud, Université Paris-Saclay, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France., Gharsalli T; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France.; Inovarion, Paris, France., Guix C; Apoptosis, Cancer and Development Laboratory-Equipe labellisée 'La Ligue', LabEx DEVweCAN, Institut Convergence PLAsCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon1, Centre Léon Bérard, Lyon, France., Ducarouge B; NETRIS Pharma, Lyon, France., Neururer V; Apoptosis, Cancer and Development Laboratory-Equipe labellisée 'La Ligue', LabEx DEVweCAN, Institut Convergence PLAsCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon1, Centre Léon Bérard, Lyon, France., Basili I; Institut Curie, PSL Research University, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France.; Université Paris Sud, Université Paris-Saclay, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France.; Department of Molecular Medicine, University La Sapienza, Rome, Italy.; Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy., Mercier AL; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France., Yu H; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France., Forget A; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France., Indersie E; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France., Leboucher S; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France; Institut Curie, Centre de Recherche, Plateforme d'Histologie, Orsay, France., Souphron J; Institut Curie, PSL Research University, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France.; Université Paris Sud, Université Paris-Saclay, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France., Okonechnikov K; Hopp Children's Cancer Center Heidelberg (KiTZ), Division of Pediatric Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Wang W; Department of Biochemistry and Cellular Biology, National Center of Neurology and Psychiatry, Tokyo, Japan.; Department of Neuro-oncology, Institute of Brain Science, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Kawauchi D; Department of Biochemistry and Cellular Biology, National Center of Neurology and Psychiatry, Tokyo, Japan.; Department of Neuro-oncology, Institute of Brain Science, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Wainwright BJ; UQ Diamantina Institute, The University of Queensland, Brisbane, QLD, Australia., Frappaz D; Department of Neuro-Oncology, Centre Léon Bérard, Institut d'Hématologie et Oncologie Pédiatrique et Adulte, Lyon, France., Varlet P; Department of Neuropathology, GHU Paris Psychiatrie Neurosciences, Sainte-Anne Hospital, Paris, France., Dufour C; Department of Pediatric and Adolescent Oncology, Institut Gustave-Roussy, Villejuif, France., Beccaria K; Pediatric Neurosurgery, APHP, Hôpital Necker, Université de Paris Cité, Paris, France., Blauwblomme T; Pediatric Neurosurgery, APHP, Hôpital Necker, Université de Paris Cité, Paris, France., Martignetti L; Institut Curie, PSL Research University, INSERM U900, Paris, France.; Mines Paris Tech, Fontainebleau, France., Di Marcotullio L; Department of Molecular Medicine, University La Sapienza, Rome, Italy.; Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy., Puget S; Pediatric Neurosurgery, APHP, Hôpital Necker, Université de Paris Cité, Paris, France., Doz F; Université Paris Cité, Paris, France.; SIREDO Oncology Center (Care, Innovation and Research for Children and AYA with Cancer), Institut Curie, Paris, France., Bourdeaut F; Université Paris Cité, Paris, France.; SIREDO Oncology Center (Care, Innovation and Research for Children and AYA with Cancer), Institut Curie, Paris, France.; Institut Curie, INSERM U1330. Children's Oncology Research Unit (CONCERT), Paris, France., Masliah-Planchon J; SIREDO Oncology Center (Care, Innovation and Research for Children and AYA with Cancer), Institut Curie, Paris, France.; PSL Research University, Institut Curie Hospital, Laboratory of Somatic Genetics, Paris, France., Gershon TR; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Mehlen P; Apoptosis, Cancer and Development Laboratory-Equipe labellisée 'La Ligue', LabEx DEVweCAN, Institut Convergence PLAsCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon1, Centre Léon Bérard, Lyon, France. patrick.mehlen@lyon.unicancer.fr.; NETRIS Pharma, Lyon, France. patrick.mehlen@lyon.unicancer.fr., Ayrault O; Institut Curie, PSL Research University, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France. olivier.ayrault@curie.fr.; Université Paris Sud, Université Paris-Saclay, INSERM U1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France. olivier.ayrault@curie.fr. |
| Source: | Nature communications [Nat Commun] 2025 Jun 03; Vol. 16 (1), pp. 5137. Date of Electronic Publication: 2025 Jun 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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