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1-Deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway.

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Title: 1-Deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway.
Authors: Tsai YT; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093., Lipp NF; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093., Seidel O; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093., Varma R; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093., Laguerre A; Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.; Salk Institute of Biological Studies, 10010 N Torrey Pines Road, La Jolla, CA 92037., Solorio-Kirpichyan K; Department of Cell and Developmental Biology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093., Wong A; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093., Brea RJ; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.; CICA - Centro Interdisciplinar de Química e Bioloxía e Departamento de Química, Facultade de Ciencias, Universidade da Coruña, Rúa As Carballeiras, 15701 A Coruña, Spain., McGregor GH; Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.; Salk Institute of Biological Studies, 10010 N Torrey Pines Road, La Jolla, CA 92037., Cordes T; Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.; Salk Institute of Biological Studies, 10010 N Torrey Pines Road, La Jolla, CA 92037., Devaraj NK; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093., Kuerschner L; Life & Medical Sciences Institute, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany., Neal S; Department of Cell and Developmental Biology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093., Metallo CM; Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.; Salk Institute of Biological Studies, 10010 N Torrey Pines Road, La Jolla, CA 92037., Budin I; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 May 17. Date of Electronic Publication: 2025 May 17.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Tsai+YT%22">Tsai YT</searchLink>; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Lipp+NF%22">Lipp NF</searchLink>; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Seidel+O%22">Seidel O</searchLink>; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Varma+R%22">Varma R</searchLink>; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Laguerre+A%22">Laguerre A</searchLink>; Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.; Salk Institute of Biological Studies, 10010 N Torrey Pines Road, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Solorio-Kirpichyan+K%22">Solorio-Kirpichyan K</searchLink>; Department of Cell and Developmental Biology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Wong+A%22">Wong A</searchLink>; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Brea+RJ%22">Brea RJ</searchLink>; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.; CICA - Centro Interdisciplinar de Química e Bioloxía e Departamento de Química, Facultade de Ciencias, Universidade da Coruña, Rúa As Carballeiras, 15701 A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22McGregor+GH%22">McGregor GH</searchLink>; Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.; Salk Institute of Biological Studies, 10010 N Torrey Pines Road, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Cordes+T%22">Cordes T</searchLink>; Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.; Salk Institute of Biological Studies, 10010 N Torrey Pines Road, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Devaraj+NK%22">Devaraj NK</searchLink>; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Kuerschner+L%22">Kuerschner L</searchLink>; Life & Medical Sciences Institute, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Neal+S%22">Neal S</searchLink>; Department of Cell and Developmental Biology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Metallo+CM%22">Metallo CM</searchLink>; Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.; Salk Institute of Biological Studies, 10010 N Torrey Pines Road, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Budin+I%22">Budin I</searchLink>; Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
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