LC-MS/MS proteomics identifies plasma proteins related to cognition over 9-year follow-up.

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Title: LC-MS/MS proteomics identifies plasma proteins related to cognition over 9-year follow-up.
Authors: Adegboye HA; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Medical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Patterson KL; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Libby J; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Sun Y; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Zhang P; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Liu D; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Robb WH; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Peterson AJ; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Cole KR; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Arul AB; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Oliver NC; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Whitaker MD; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Pechman KR; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Dumitrescu L; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Bolton CJ; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Paris Brain Institute, ICM, Hôpital Pitié, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, China., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, InnoHK, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA., Hohman TJ; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Robinson RAS; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Jefferson AL; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Jun; Vol. 21 (6), pp. e70276.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
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  Data: LC-MS/MS proteomics identifies plasma proteins related to cognition over 9-year follow-up.
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  Data: <searchLink fieldCode="AU" term="%22Adegboye+HA%22">Adegboye HA</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Medical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Patterson+KL%22">Patterson KL</searchLink>; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Libby+J%22">Libby J</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Robb+WH%22">Robb WH</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Peterson+AJ%22">Peterson AJ</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Cole+KR%22">Cole KR</searchLink>; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Arul+AB%22">Arul AB</searchLink>; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Oliver+NC%22">Oliver NC</searchLink>; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Whitaker+MD%22">Whitaker MD</searchLink>; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Pechman+KR%22">Pechman KR</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Dumitrescu+L%22">Dumitrescu L</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Bolton+CJ%22">Bolton CJ</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Paris Brain Institute, ICM, Hôpital Pitié, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, InnoHK, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Hohman+TJ%22">Hohman TJ</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Robinson+RAS%22">Robinson RAS</searchLink>; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Jefferson+AL%22">Jefferson AL</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
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  Data: <searchLink fieldCode="JN" term="%22101231978%22">Alzheimer's & dementia : the journal of the Alzheimer's Association</searchLink> [Alzheimers Dement] 2025 Jun; Vol. 21 (6), pp. e70276.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
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