Deep-learning-enabled multi-omics analyses for prediction of future metastasis in cancer.

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Title: Deep-learning-enabled multi-omics analyses for prediction of future metastasis in cancer.
Authors: Wang X; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA., Duan M; Division of Mathematical Sciences, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore City, 637371, Singapore., Su PL; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 494 Biomedical Research Tower, 460 W 10th Ave., Columbus, OH 43210, USA.; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, 138 Shengli Rd, Tainan 704, Taiwan., Li J; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA., Krull J; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA., Jin J; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA., Chen H; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA., Sun Y; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA., Wu W; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA., He K; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 494 Biomedical Research Tower, 460 W 10th Ave., Columbus, OH 43210, USA., Carpenter RL; Medical Sciences, Indiana University, Bloomington, IN 47405.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202.; Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202., Zhang C; Department of Biomedical Engineering, School of Medicine, Oregon Health and Sciences University, USA., Cao S; Department of Biomedical Engineering, School of Medicine, Oregon Health and Sciences University, USA., Xu D; Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO 65211, USA.; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA., Wang G; Center for Bioinformatics and Computational Biology, Houston Methodist Research Institute, Houston, TX 77030, USA.; Department of Cardiothoracic Surgery, Weill Cornell Medicine, Cornell University, New York, NY 10065, USA., Li L; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA., Xin G; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA., Carbone DP; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 494 Biomedical Research Tower, 460 W 10th Ave., Columbus, OH 43210, USA., Li Z; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA., Ma Q; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 May 22. Date of Electronic Publication: 2025 May 22.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Deep-learning-enabled multi-omics analyses for prediction of future metastasis in cancer.
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  Data: <searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.<br /><searchLink fieldCode="AU" term="%22Duan+M%22">Duan M</searchLink>; Division of Mathematical Sciences, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore City, 637371, Singapore.<br /><searchLink fieldCode="AU" term="%22Su+PL%22">Su PL</searchLink>; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 494 Biomedical Research Tower, 460 W 10th Ave., Columbus, OH 43210, USA.; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, 138 Shengli Rd, Tainan 704, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Krull+J%22">Krull J</searchLink>; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.<br /><searchLink fieldCode="AU" term="%22Jin+J%22">Jin J</searchLink>; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Wu+W%22">Wu W</searchLink>; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22He+K%22">He K</searchLink>; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 494 Biomedical Research Tower, 460 W 10th Ave., Columbus, OH 43210, USA.<br /><searchLink fieldCode="AU" term="%22Carpenter+RL%22">Carpenter RL</searchLink>; Medical Sciences, Indiana University, Bloomington, IN 47405.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202.; Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Biomedical Engineering, School of Medicine, Oregon Health and Sciences University, USA.<br /><searchLink fieldCode="AU" term="%22Cao+S%22">Cao S</searchLink>; Department of Biomedical Engineering, School of Medicine, Oregon Health and Sciences University, USA.<br /><searchLink fieldCode="AU" term="%22Xu+D%22">Xu D</searchLink>; Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO 65211, USA.; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.<br /><searchLink fieldCode="AU" term="%22Wang+G%22">Wang G</searchLink>; Center for Bioinformatics and Computational Biology, Houston Methodist Research Institute, Houston, TX 77030, USA.; Department of Cardiothoracic Surgery, Weill Cornell Medicine, Cornell University, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Xin+G%22">Xin G</searchLink>; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Carbone+DP%22">Carbone DP</searchLink>; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 494 Biomedical Research Tower, 460 W 10th Ave., Columbus, OH 43210, USA.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.<br /><searchLink fieldCode="AU" term="%22Ma+Q%22">Ma Q</searchLink>; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
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