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Clinical Significance of Somatic PIK3CA and MAP3K3 Mutations in Cerebral and Spinal Cavernous Malformations.

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Title: Clinical Significance of Somatic PIK3CA and MAP3K3 Mutations in Cerebral and Spinal Cavernous Malformations.
Authors: Hongo H; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Miyawaki S; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan. smiya-nsu@m.u-tokyo.ac.jp., Takai K; Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital, Fuchu, Japan., Ono H; Department of Neurosurgery, Fuji Brain Institute and Hospital, Fujinomiya, Japan., Shimizu M; Department of Neurosurgery, Kanto Neurosurgical Hospital, Kumagaya, Japan., Matsukawa T; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Ogawa S; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Teranishi Y; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Kiyofuji S; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Ohara K; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Ishigami D; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Sakai Y; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Torazawa S; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Hirano Y; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Shimada D; Department of Neurosurgery, Kyorin University Faculty of Medicine, Mitaka, Japan., Kunii N; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Neurosurgery, Jichi Medical University, Shimotsuke, Japan., Shimada S; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Mitsui J; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Precision Medicine Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Katoh H; Department of Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Komura D; Department of Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Nakatomi H; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Ishikawa S; Department of Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Saito N; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Source: Translational stroke research [Transl Stroke Res] 2025 Dec; Vol. 16 (6), pp. 1966-1974. Date of Electronic Publication: 2025 Jun 06.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101517297 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1868-601X (Electronic) Linking ISSN: 18684483 NLM ISO Abbreviation: Transl Stroke Res Subsets: MEDLINE
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  Data: Clinical Significance of Somatic PIK3CA and MAP3K3 Mutations in Cerebral and Spinal Cavernous Malformations.
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  Data: <searchLink fieldCode="AU" term="%22Hongo+H%22">Hongo H</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Miyawaki+S%22">Miyawaki S</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan. smiya-nsu@m.u-tokyo.ac.jp.<br /><searchLink fieldCode="AU" term="%22Takai+K%22">Takai K</searchLink>; Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital, Fuchu, Japan.<br /><searchLink fieldCode="AU" term="%22Ono+H%22">Ono H</searchLink>; Department of Neurosurgery, Fuji Brain Institute and Hospital, Fujinomiya, Japan.<br /><searchLink fieldCode="AU" term="%22Shimizu+M%22">Shimizu M</searchLink>; Department of Neurosurgery, Kanto Neurosurgical Hospital, Kumagaya, Japan.<br /><searchLink fieldCode="AU" term="%22Matsukawa+T%22">Matsukawa T</searchLink>; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ogawa+S%22">Ogawa S</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Teranishi+Y%22">Teranishi Y</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kiyofuji+S%22">Kiyofuji S</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ohara+K%22">Ohara K</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ishigami+D%22">Ishigami D</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Sakai+Y%22">Sakai Y</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Torazawa+S%22">Torazawa S</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hirano+Y%22">Hirano Y</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shimada+D%22">Shimada D</searchLink>; Department of Neurosurgery, Kyorin University Faculty of Medicine, Mitaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kunii+N%22">Kunii N</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Neurosurgery, Jichi Medical University, Shimotsuke, Japan.<br /><searchLink fieldCode="AU" term="%22Shimada+S%22">Shimada S</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Mitsui+J%22">Mitsui J</searchLink>; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Precision Medicine Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Katoh+H%22">Katoh H</searchLink>; Department of Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Komura+D%22">Komura D</searchLink>; Department of Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Nakatomi+H%22">Nakatomi H</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ishikawa+S%22">Ishikawa S</searchLink>; Department of Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Saito+N%22">Saito N</searchLink>; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101517297%22">Translational stroke research</searchLink> [Transl Stroke Res] 2025 Dec; Vol. 16 (6), pp. 1966-1974. <i>Date of Electronic Publication: </i>2025 Jun 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101517297 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1868-601X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218684483%22">18684483 </searchLink><i>NLM ISO Abbreviation: </i>Transl Stroke Res <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s12975-025-01360-2
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        Text: English
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        StartPage: 1966
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      – TitleFull: Clinical Significance of Somatic PIK3CA and MAP3K3 Mutations in Cerebral and Spinal Cavernous Malformations.
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              Text: 2025 Dec
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