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Epigenetic mechanisms underlying variation of IL-6, a well-established inflammation biomarker and risk factor for cardiovascular disease.

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Title: Epigenetic mechanisms underlying variation of IL-6, a well-established inflammation biomarker and risk factor for cardiovascular disease.
Authors: Lundin JI; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA. Electronic address: Jlundin2@fredhutch.org., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA. Electronic address: upeters@fredhutch.org., Hu Y; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA. Electronic address: yhu23@fredhutch.org., Ammous F; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA. Electronic address: fammous@umich.edu., Benjamin EJ; Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston University School of Public Health, Boston, MA, USA. Electronic address: emelia@bu.edu., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA. Electronic address: joshbis@uw.edu., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA. Electronic address: jeco@uw.edu., Cushman M; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA. Electronic address: mary.cushman@uvm.edu., Fuller H; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA. Electronic address: hfuller@fredhutch.org., Gignoux C; Quantitative Biology, University of Colorado, Boulder, CO, USA. Electronic address: chris.gignoux@cuanschutz.edu., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA. Electronic address: xguo@lundquist.org., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA. Electronic address: jhaessle@WHI.org., Haiman C; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: christopher.haiman@med.usc.edu., Joehanes R; Population Sciences Branch, National Heart, Lung, and Blood Institute of the National Institutes of Health, Bethesda, MD, USA; Framingham Heart Study, Framingham, MA, USA. Electronic address: roby.joehanes@nih.gov., Kasela S; New York Genome Center, New York, NY, USA. Electronic address: silva.kasela@gmail.com., Kenny E; Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: eimear.kenny@mssm.edu., Lappalainen T; New York Genome Center, New York, NY, USA. Electronic address: tlappalainen@nygenome.org., Levy D; Population Sciences Branch, National Heart, Lung, and Blood Institute of the National Institutes of Health, Bethesda, MD, USA. Electronic address: levyd@nhlbi.nih.gov., Liu C; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA. Electronic address: liuc@bu.edu., Liu Y; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA. Electronic address: yongmei.liu@duke.edu., Loos RJF; Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: ruth.loos@mssm.edu., Matise T; Department of Genetics, Rutgers University, New Brunswick, NJ, USA. Electronic address: matise@rutgers.edu., North KE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA. Electronic address: kari_north@unc.edu., Park SL; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA. Electronic address: lpark@cc.hawaii.edu., Ratliff SM; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA. Electronic address: ratliffs@umich.edu., Reiner A; Department of Epidemiology, University of Washington, Seattle, WA, USA. Electronic address: apreiner@uw.edu., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA. Electronic address: ssr4n@virginia.edu., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA. Electronic address: jrotter@lundquist.org., Smith JA; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA. Electronic address: smjenn@umich.edu., Sotoodehnia N; Cardiovascular Health Research Unit, Harborview Medical Center, Seattle, WA, USA. Electronic address: nsotoo@uw.edu., Tracy R; Department of Pathology and Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA. Electronic address: Russell.Tracy@uvm.edu., Van den Berg D; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: dvandenb@usc.edu., Ye T; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA. Electronic address: tingye1@uw.edu., Zhao W; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA. Electronic address: zhaowei@umich.edu., Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA. Electronic address: laura_raffield@unc.edu., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA. Electronic address: clk@fredhutch.org.
Corporate Authors: PAGE Study
Source: Atherosclerosis [Atherosclerosis] 2025 Aug; Vol. 407, pp. 120219. Date of Electronic Publication: 2025 May 20.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Epigenetic mechanisms underlying variation of IL-6, a well-established inflammation biomarker and risk factor for cardiovascular disease.
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  Data: <searchLink fieldCode="AU" term="%22Lundin+JI%22">Lundin JI</searchLink>; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA. Electronic address: Jlundin2@fredhutch.org.<br /><searchLink fieldCode="AU" term="%22Peters+U%22">Peters U</searchLink>; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA. Electronic address: upeters@fredhutch.org.<br /><searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink>; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA. Electronic address: yhu23@fredhutch.org.<br /><searchLink fieldCode="AU" term="%22Ammous+F%22">Ammous F</searchLink>; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA. Electronic address: fammous@umich.edu.<br /><searchLink fieldCode="AU" term="%22Benjamin+EJ%22">Benjamin EJ</searchLink>; Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston University School of Public Health, Boston, MA, USA. Electronic address: emelia@bu.edu.<br /><searchLink fieldCode="AU" term="%22Bis+JC%22">Bis JC</searchLink>; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA. Electronic address: joshbis@uw.edu.<br /><searchLink fieldCode="AU" term="%22Brody+JA%22">Brody JA</searchLink>; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA. Electronic address: jeco@uw.edu.<br /><searchLink fieldCode="AU" term="%22Cushman+M%22">Cushman M</searchLink>; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA. 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Electronic address: eimear.kenny@mssm.edu.<br /><searchLink fieldCode="AU" term="%22Lappalainen+T%22">Lappalainen T</searchLink>; New York Genome Center, New York, NY, USA. Electronic address: tlappalainen@nygenome.org.<br /><searchLink fieldCode="AU" term="%22Levy+D%22">Levy D</searchLink>; Population Sciences Branch, National Heart, Lung, and Blood Institute of the National Institutes of Health, Bethesda, MD, USA. Electronic address: levyd@nhlbi.nih.gov.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA. Electronic address: liuc@bu.edu.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA. Electronic address: yongmei.liu@duke.edu.<br /><searchLink fieldCode="AU" term="%22Loos+RJF%22">Loos RJF</searchLink>; Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: ruth.loos@mssm.edu.<br /><searchLink fieldCode="AU" term="%22Matise+T%22">Matise T</searchLink>; Department of Genetics, Rutgers University, New Brunswick, NJ, USA. Electronic address: matise@rutgers.edu.<br /><searchLink fieldCode="AU" term="%22North+KE%22">North KE</searchLink>; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA. Electronic address: kari_north@unc.edu.<br /><searchLink fieldCode="AU" term="%22Park+SL%22">Park SL</searchLink>; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA. Electronic address: lpark@cc.hawaii.edu.<br /><searchLink fieldCode="AU" term="%22Ratliff+SM%22">Ratliff SM</searchLink>; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA. Electronic address: ratliffs@umich.edu.<br /><searchLink fieldCode="AU" term="%22Reiner+A%22">Reiner A</searchLink>; Department of Epidemiology, University of Washington, Seattle, WA, USA. Electronic address: apreiner@uw.edu.<br /><searchLink fieldCode="AU" term="%22Rich+SS%22">Rich SS</searchLink>; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA. Electronic address: ssr4n@virginia.edu.<br /><searchLink fieldCode="AU" term="%22Rotter+JI%22">Rotter JI</searchLink>; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA. Electronic address: jrotter@lundquist.org.<br /><searchLink fieldCode="AU" term="%22Smith+JA%22">Smith JA</searchLink>; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA. Electronic address: smjenn@umich.edu.<br /><searchLink fieldCode="AU" term="%22Sotoodehnia+N%22">Sotoodehnia N</searchLink>; Cardiovascular Health Research Unit, Harborview Medical Center, Seattle, WA, USA. Electronic address: nsotoo@uw.edu.<br /><searchLink fieldCode="AU" term="%22Tracy+R%22">Tracy R</searchLink>; Department of Pathology and Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA. Electronic address: Russell.Tracy@uvm.edu.<br /><searchLink fieldCode="AU" term="%22Van+den+Berg+D%22">Van den Berg D</searchLink>; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: dvandenb@usc.edu.<br /><searchLink fieldCode="AU" term="%22Ye+T%22">Ye T</searchLink>; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA. 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