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A Novel Live-Cell Microscopy Platform for Real-Time Visualization of 53BP1 Foci Dynamics and Accurate Dosimetry in Proton Therapy.

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Title: A Novel Live-Cell Microscopy Platform for Real-Time Visualization of 53BP1 Foci Dynamics and Accurate Dosimetry in Proton Therapy.
Authors: Heemskerk T; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address: t.heemskerk.1@erasmusmc.nl., Rovituso M; Research & Development, HollandPTC, Delft, the Netherlands. Electronic address: m.rovituso@hollandptc.nl., van der Wal E; Research & Development, HollandPTC, Delft, the Netherlands. Electronic address: ernst@lyla.systems., Kremers GJ; Optical Imaging Centre, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address: g.kremers@erasmusmc.nl., Slotman JA; Optical Imaging Centre, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address: j.slotman@erasmusmc.nl., Hoogeman M; Department of Radiotherapy, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, the Netherlands; Department of Medical Physics & Informatics, HollandPTC, Delft, the Netherlands. Electronic address: m.hoogeman@hollandptc.nl., Essers J; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Radiotherapy, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, the Netherlands; Department of Vascular Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address: j.essers@erasmusmc.nl.
Source: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) [Phys Med] 2025 Jul; Vol. 135, pp. 105020. Date of Electronic Publication: 2025 Jun 05.
Publication Type: Journal Article
Journal Info: Publisher: Istituti Editoriali e Poligrafici Internazionali Country of Publication: Italy NLM ID: 9302888 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1724-191X (Electronic) Linking ISSN: 11201797 NLM ISO Abbreviation: Phys Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Novel Live-Cell Microscopy Platform for Real-Time Visualization of 53BP1 Foci Dynamics and Accurate Dosimetry in Proton Therapy.
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  Data: <searchLink fieldCode="AU" term="%22Heemskerk+T%22">Heemskerk T</searchLink>; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address: t.heemskerk.1@erasmusmc.nl.<br /><searchLink fieldCode="AU" term="%22Rovituso+M%22">Rovituso M</searchLink>; Research & Development, HollandPTC, Delft, the Netherlands. Electronic address: m.rovituso@hollandptc.nl.<br /><searchLink fieldCode="AU" term="%22van+der+Wal+E%22">van der Wal E</searchLink>; Research & Development, HollandPTC, Delft, the Netherlands. Electronic address: ernst@lyla.systems.<br /><searchLink fieldCode="AU" term="%22Kremers+GJ%22">Kremers GJ</searchLink>; Optical Imaging Centre, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address: g.kremers@erasmusmc.nl.<br /><searchLink fieldCode="AU" term="%22Slotman+JA%22">Slotman JA</searchLink>; Optical Imaging Centre, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address: j.slotman@erasmusmc.nl.<br /><searchLink fieldCode="AU" term="%22Hoogeman+M%22">Hoogeman M</searchLink>; Department of Radiotherapy, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, the Netherlands; Department of Medical Physics & Informatics, HollandPTC, Delft, the Netherlands. Electronic address: m.hoogeman@hollandptc.nl.<br /><searchLink fieldCode="AU" term="%22Essers+J%22">Essers J</searchLink>; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Radiotherapy, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, the Netherlands; Department of Vascular Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address: j.essers@erasmusmc.nl.
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  Data: <searchLink fieldCode="JN" term="%229302888%22">Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)</searchLink> [Phys Med] 2025 Jul; Vol. 135, pp. 105020. <i>Date of Electronic Publication: </i>2025 Jun 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Istituti+Editoriali+e+Poligrafici+Internazionali%22">Istituti Editoriali e Poligrafici Internazionali </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>9302888 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1724-191X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211201797%22">11201797 </searchLink><i>NLM ISO Abbreviation: </i>Phys Med <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.ejmp.2025.105020
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              Text: 2025 Jul
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