An on-chip deformability checker demonstrates that the severity of iron deficiency is associated with increased deformability of red blood cells.

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Title: An on-chip deformability checker demonstrates that the severity of iron deficiency is associated with increased deformability of red blood cells.
Authors: Kajitani K; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan., Ohtani T; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan. ohtani@cardiology.med.osaka-u.ac.jp., Higuchi R; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan., Chimura M; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan., Sera F; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan., Tsai CD; Department of Mechanical Engineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan., Ueda Y; Department of Hematology and Oncology, Graduate School of Medicine, The University of Osaka, Suita, Japan., Nishimura JI; Department of Hematology and Oncology, Graduate School of Medicine, The University of Osaka, Suita, Japan., Sakata Y; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan.
Source: Scientific reports [Sci Rep] 2025 Jun 06; Vol. 15 (1), pp. 19994. Date of Electronic Publication: 2025 Jun 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An on-chip deformability checker demonstrates that the severity of iron deficiency is associated with increased deformability of red blood cells.
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  Data: <searchLink fieldCode="AU" term="%22Kajitani+K%22">Kajitani K</searchLink>; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Ohtani+T%22">Ohtani T</searchLink>; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan. ohtani@cardiology.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Higuchi+R%22">Higuchi R</searchLink>; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Chimura+M%22">Chimura M</searchLink>; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Sera+F%22">Sera F</searchLink>; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Tsai+CD%22">Tsai CD</searchLink>; Department of Mechanical Engineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ueda+Y%22">Ueda Y</searchLink>; Department of Hematology and Oncology, Graduate School of Medicine, The University of Osaka, Suita, Japan.<br /><searchLink fieldCode="AU" term="%22Nishimura+JI%22">Nishimura JI</searchLink>; Department of Hematology and Oncology, Graduate School of Medicine, The University of Osaka, Suita, Japan.<br /><searchLink fieldCode="AU" term="%22Sakata+Y%22">Sakata Y</searchLink>; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka, Suita, 565-0871, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Jun 06; Vol. 15 (1), pp. 19994. <i>Date of Electronic Publication: </i>2025 Jun 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41598-025-05483-2
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              Text: 2025 Jun 06
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