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GX-I7, a long-acting IL-7, safely and effectively increased peripheral CD8+/CD4+ T cells and TILs in patients with locally advanced or metastatic solid tumours.

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Title: GX-I7, a long-acting IL-7, safely and effectively increased peripheral CD8+/CD4+ T cells and TILs in patients with locally advanced or metastatic solid tumours.
Authors: Kim GM; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea., Kim S; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea.; Division of Hematology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea., Lee MA; Division of Medical Oncology, Seoul St, Mary's Hospital, The catholic University of Korea, Seoul, Korea., Byun MS; Genexine, Inc., Seoul, Korea., Choi D; NeoImmuneTech, Inc., Rockville, MD, USA., Yang SH; NeoImmuneTech, Inc., Rockville, MD, USA., Woo J; Genexine, Inc., Seoul, Korea., Sung YC; Genexine, Inc., Seoul, Korea., Shin EC; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea., Park SH; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea. park3@kaist.ac.kr., Kim TW; Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. twkimmd@amc.seoul.kr., Sohn J; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea. ONCOSOHN@yuhs.ac.
Source: British journal of cancer [Br J Cancer] 2025 Sep; Vol. 133 (4), pp. 524-532. Date of Electronic Publication: 2025 Jun 09.
Publication Type: Journal Article; Clinical Trial, Phase I; Multicenter Study
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: GX-I7, a long-acting IL-7, safely and effectively increased peripheral CD8<superscript>+</superscript>/CD4<superscript>+</superscript> T cells and TILs in patients with locally advanced or metastatic solid tumours.
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  Data: <searchLink fieldCode="AU" term="%22Kim+GM%22">Kim GM</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea.; Division of Hematology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+MA%22">Lee MA</searchLink>; Division of Medical Oncology, Seoul St, Mary's Hospital, The catholic University of Korea, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Byun+MS%22">Byun MS</searchLink>; Genexine, Inc., Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Choi+D%22">Choi D</searchLink>; NeoImmuneTech, Inc., Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Yang+SH%22">Yang SH</searchLink>; NeoImmuneTech, Inc., Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Woo+J%22">Woo J</searchLink>; Genexine, Inc., Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Sung+YC%22">Sung YC</searchLink>; Genexine, Inc., Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Shin+EC%22">Shin EC</searchLink>; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea.<br /><searchLink fieldCode="AU" term="%22Park+SH%22">Park SH</searchLink>; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea. park3@kaist.ac.kr.<br /><searchLink fieldCode="AU" term="%22Kim+TW%22">Kim TW</searchLink>; Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. twkimmd@amc.seoul.kr.<br /><searchLink fieldCode="AU" term="%22Sohn+J%22">Sohn J</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea. ONCOSOHN@yuhs.ac.
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  Data: <searchLink fieldCode="JN" term="%220370635%22">British journal of cancer</searchLink> [Br J Cancer] 2025 Sep; Vol. 133 (4), pp. 524-532. <i>Date of Electronic Publication: </i>2025 Jun 09.
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  Data: Journal Article; Clinical Trial, Phase I; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+on+behalf+of+Cancer+Research+UK%22">Nature Publishing Group on behalf of Cancer Research UK </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0370635 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-1827 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070920%22">00070920 </searchLink><i>NLM ISO Abbreviation: </i>Br J Cancer <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40490502
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        Value: 10.1038/s41416-025-03069-3
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              Text: 2025 Sep
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