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Computational investigation unveils pathogenic LIG3 non-synonymous mutations and therapeutic targets in acute myeloid leukemia.

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Title: Computational investigation unveils pathogenic LIG3 non-synonymous mutations and therapeutic targets in acute myeloid leukemia.
Authors: Hossen MA; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh., Jahan UMS; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh., Hossain MA; Department of Biochemistry and Biotechnology, Khwaja Yunus Ali University, Sirajganj, Bangladesh., Asif KH; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh., Rahman A; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh., Ahmed S; Department of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh., Uddin MM; Department of Biotechnology, Bangladesh Agricultural University, Mymensingh, Bangladesh., Amin MF; Department of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh., Barik MA; Department of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh., Islam MJ; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh., Kamruzzaman M; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh., Hasnat S; Molecular Biology and Bioinformatics Laboratory, Department of Gynecology, Obstetrics and Reproductive Health, Gazipur Agricultural University, Gazipur, Bangladesh.; Institute of Biotechnology and Genetic Engineering, Gazipur Agricultural University, Gazipur, Bangladesh., Uddin MN; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh., Islam T; Institute of Biotechnology and Genetic Engineering, Gazipur Agricultural University, Gazipur, Bangladesh., Hoque MN; Molecular Biology and Bioinformatics Laboratory, Department of Gynecology, Obstetrics and Reproductive Health, Gazipur Agricultural University, Gazipur, Bangladesh.
Source: PloS one [PLoS One] 2025 Jun 10; Vol. 20 (6), pp. e0320550. Date of Electronic Publication: 2025 Jun 10 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Computational investigation unveils pathogenic LIG3 non-synonymous mutations and therapeutic targets in acute myeloid leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Hossen+MA%22">Hossen MA</searchLink>; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Jahan+UMS%22">Jahan UMS</searchLink>; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Hossain+MA%22">Hossain MA</searchLink>; Department of Biochemistry and Biotechnology, Khwaja Yunus Ali University, Sirajganj, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Asif+KH%22">Asif KH</searchLink>; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Rahman+A%22">Rahman A</searchLink>; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Ahmed+S%22">Ahmed S</searchLink>; Department of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Uddin+MM%22">Uddin MM</searchLink>; Department of Biotechnology, Bangladesh Agricultural University, Mymensingh, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Amin+MF%22">Amin MF</searchLink>; Department of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Barik+MA%22">Barik MA</searchLink>; Department of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Islam+MJ%22">Islam MJ</searchLink>; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Kamruzzaman+M%22">Kamruzzaman M</searchLink>; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Hasnat+S%22">Hasnat S</searchLink>; Molecular Biology and Bioinformatics Laboratory, Department of Gynecology, Obstetrics and Reproductive Health, Gazipur Agricultural University, Gazipur, Bangladesh.; Institute of Biotechnology and Genetic Engineering, Gazipur Agricultural University, Gazipur, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Uddin+MN%22">Uddin MN</searchLink>; Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Islam+T%22">Islam T</searchLink>; Institute of Biotechnology and Genetic Engineering, Gazipur Agricultural University, Gazipur, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Hoque+MN%22">Hoque MN</searchLink>; Molecular Biology and Bioinformatics Laboratory, Department of Gynecology, Obstetrics and Reproductive Health, Gazipur Agricultural University, Gazipur, Bangladesh.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2025 Jun 10; Vol. 20 (6), pp. e0320550. <i>Date of Electronic Publication: </i>2025 Jun 10 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101285081 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-6203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219326203%22">19326203 </searchLink><i>NLM ISO Abbreviation: </i>PLoS One <i>Subsets: </i>MEDLINE
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