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Prediction of outcomes following intravenous thrombolysis in patients with acute ischemic stroke using serum UCH-L1, S100β, and NSE: a multicenter prospective cohort study employing machine learning methods.

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Title: Prediction of outcomes following intravenous thrombolysis in patients with acute ischemic stroke using serum UCH-L1, S100β, and NSE: a multicenter prospective cohort study employing machine learning methods.
Authors: Luo MY; Stroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China., Qu Y; Stroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China., Zhang P; Stroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China., Abuduxukuer R; Stroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China., Wang LJ; Department of Neurology, Songyuan Central Hospital, Songyuan, China., Yang LC; Department of Neurology, Jilin Neuropsychiatric Hospital, Siping, China., Li ZG; Stroke Center, Department of Neurology, Siping Central People's Hospital, Siping, China., Liu XD; Department of Neurosurgery, Tonghua City Vascular Disease Hospital and Dongchang District People's Hospital, Tonghua, China., Han C; Department of Neurology, Songyuan Jilin Oilfield Hospital, Songyuan, China., Li D; Stroke Center, Department of Neurology, Dehuishi People's Hospital, Changchun, China., Wang WJ; Department of Neurology, Affiliated Hospital of Jilin Medical College, Jilin, China., Lv DP; Department of Neurology, Songyuan Hospital of Integrated Traditional Chinese and Western Medicine, Songyuan, China., Liu M; Stroke Center, Department of Neurology, Qianguoerros Mongolian Autonomous County Hospital, Songyuan, China., Gao J; Department of Neurology, Affiliated Hospital of Jilin Medical College, Jilin, China., Xu J; Department of Neurology, Jilin City Hospital of Chemical Industry, Jilin, China., Jiang Y; Department of Neurology, Changchun People's Hospital, Changchun, China.; Department of Neurology, Changchun Second Hospital, Changchun, China., Chen HN; Department of Neurology, Dongliao First People's Hospital, Liaoyuan, China., Li FJ; Department of Neurology, Jilin People's Hospital, Jilin, China., Sun LM; Department of Neurology, Jilin City Hospital of Chemical Industry, Jilin, China., Sun QD; Department of Neurology, Jilin City Hospital of Chemical Industry, Jilin, China., Qi Y; Department of Neurology, Jilin Province People's Hospital, Changchun, China., Sun SY; Stroke Center, Department of Neurology, Jilin Central General Hospital, Jilin, China., Zhang Y; Department of Neurology, Jilin Province People's Hospital, Changchun, China., Guo ZN; Stroke Center, Department of Neurology, The First Hospital of Jilin University, No. 1, Xinmin Street, Changchun 130021, China.; Neuroscience Research Center, Department of Neurology, The First Hospital of Jilin University, No. 1, Xinmin Street, Changchun 130021, China., Yang Y; Stroke Center, Department of Neurology, The First Hospital of Jilin University, No. 1, Xinmin Street, Changchun 130021, China.; Neuroscience Research Center, Department of Neurology, The First Hospital of Jilin University, No. 1, Xinmin Street, Changchun 130021, China.
Source: Therapeutic advances in neurological disorders [Ther Adv Neurol Disord] 2025 Jun 10; Vol. 18, pp. 17562864251342429. Date of Electronic Publication: 2025 Jun 10 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: SAGE Country of Publication: England NLM ID: 101480242 Publication Model: eCollection Cited Medium: Print ISSN: 1756-2856 (Print) Linking ISSN: 17562856 NLM ISO Abbreviation: Ther Adv Neurol Disord Subsets: PubMed not MEDLINE
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  Data: Prediction of outcomes following intravenous thrombolysis in patients with acute ischemic stroke using serum UCH-L1, S100β, and NSE: a multicenter prospective cohort study employing machine learning methods.
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  Data: <searchLink fieldCode="AU" term="%22Luo+MY%22">Luo MY</searchLink>; Stroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Qu+Y%22">Qu Y</searchLink>; Stroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Stroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Abuduxukuer+R%22">Abuduxukuer R</searchLink>; Stroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Wang+LJ%22">Wang LJ</searchLink>; Department of Neurology, Songyuan Central Hospital, Songyuan, China.<br /><searchLink fieldCode="AU" term="%22Yang+LC%22">Yang LC</searchLink>; Department of Neurology, Jilin Neuropsychiatric Hospital, Siping, China.<br /><searchLink fieldCode="AU" term="%22Li+ZG%22">Li ZG</searchLink>; Stroke Center, Department of Neurology, Siping Central People's Hospital, Siping, China.<br /><searchLink fieldCode="AU" term="%22Liu+XD%22">Liu XD</searchLink>; Department of Neurosurgery, Tonghua City Vascular Disease Hospital and Dongchang District People's Hospital, Tonghua, China.<br /><searchLink fieldCode="AU" term="%22Han+C%22">Han C</searchLink>; Department of Neurology, Songyuan Jilin Oilfield Hospital, Songyuan, China.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Stroke Center, Department of Neurology, Dehuishi People's Hospital, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Wang+WJ%22">Wang WJ</searchLink>; Department of Neurology, Affiliated Hospital of Jilin Medical College, Jilin, China.<br /><searchLink fieldCode="AU" term="%22Lv+DP%22">Lv DP</searchLink>; Department of Neurology, Songyuan Hospital of Integrated Traditional Chinese and Western Medicine, Songyuan, China.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Stroke Center, Department of Neurology, Qianguoerros Mongolian Autonomous County Hospital, Songyuan, China.<br /><searchLink fieldCode="AU" term="%22Gao+J%22">Gao J</searchLink>; Department of Neurology, Affiliated Hospital of Jilin Medical College, Jilin, China.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Department of Neurology, Jilin City Hospital of Chemical Industry, Jilin, China.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Department of Neurology, Changchun People's Hospital, Changchun, China.; Department of Neurology, Changchun Second Hospital, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Chen+HN%22">Chen HN</searchLink>; Department of Neurology, Dongliao First People's Hospital, Liaoyuan, China.<br /><searchLink fieldCode="AU" term="%22Li+FJ%22">Li FJ</searchLink>; Department of Neurology, Jilin People's Hospital, Jilin, China.<br /><searchLink fieldCode="AU" term="%22Sun+LM%22">Sun LM</searchLink>; Department of Neurology, Jilin City Hospital of Chemical Industry, Jilin, China.<br /><searchLink fieldCode="AU" term="%22Sun+QD%22">Sun QD</searchLink>; Department of Neurology, Jilin City Hospital of Chemical Industry, Jilin, China.<br /><searchLink fieldCode="AU" term="%22Qi+Y%22">Qi Y</searchLink>; Department of Neurology, Jilin Province People's Hospital, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Sun+SY%22">Sun SY</searchLink>; Stroke Center, Department of Neurology, Jilin Central General Hospital, Jilin, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Neurology, Jilin Province People's Hospital, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Guo+ZN%22">Guo ZN</searchLink>; Stroke Center, Department of Neurology, The First Hospital of Jilin University, No. 1, Xinmin Street, Changchun 130021, China.; Neuroscience Research Center, Department of Neurology, The First Hospital of Jilin University, No. 1, Xinmin Street, Changchun 130021, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Stroke Center, Department of Neurology, The First Hospital of Jilin University, No. 1, Xinmin Street, Changchun 130021, China.; Neuroscience Research Center, Department of Neurology, The First Hospital of Jilin University, No. 1, Xinmin Street, Changchun 130021, China.
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