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Leptin and inflammatory pathways in the Alzheimer's disease continuum: Implications for glial activation and neuropsychiatric symptoms.

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Title: Leptin and inflammatory pathways in the Alzheimer's disease continuum: Implications for glial activation and neuropsychiatric symptoms.
Authors: Yasuno F; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan., Nakagome K; Department of Psychiatry, National Center of Neurology and Psychiatry, Kodaira, Japan., Omachi Y; Department of Psychiatry, National Center of Neurology and Psychiatry, Kodaira, Japan., Kimura Y; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan., Ogata A; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan.; Department of Pharmacy, Faculty of Pharmacy, Gifu University of Medical Science, Kani, Japan., Ikenuma H; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan., Abe J; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan., Minami H; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan., Nihashi T; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan., Yokoi K; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan., Hattori S; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan., Shimoda N; Functional Genomics Unit, Medical Genome Center, National Center for Geriatrics and Gerontology, Obu, Japan., Kasuga K; Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan., Ikeuchi T; Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan., Takeda A; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan., Sakurai T; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan., Ito K; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan., Kato T; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan.
Source: Brain, behavior, & immunity - health [Brain Behav Immun Health] 2025 May 26; Vol. 47, pp. 101018. Date of Electronic Publication: 2025 May 26 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101759062 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-3546 (Electronic) Linking ISSN: 26663546 NLM ISO Abbreviation: Brain Behav Immun Health Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Yasuno+F%22">Yasuno F</searchLink>; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Nakagome+K%22">Nakagome K</searchLink>; Department of Psychiatry, National Center of Neurology and Psychiatry, Kodaira, Japan.<br /><searchLink fieldCode="AU" term="%22Omachi+Y%22">Omachi Y</searchLink>; Department of Psychiatry, National Center of Neurology and Psychiatry, Kodaira, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+Y%22">Kimura Y</searchLink>; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Ogata+A%22">Ogata A</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan.; Department of Pharmacy, Faculty of Pharmacy, Gifu University of Medical Science, Kani, Japan.<br /><searchLink fieldCode="AU" term="%22Ikenuma+H%22">Ikenuma H</searchLink>; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Abe+J%22">Abe J</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Minami+H%22">Minami H</searchLink>; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Nihashi+T%22">Nihashi T</searchLink>; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Yokoi+K%22">Yokoi K</searchLink>; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Hattori+S%22">Hattori S</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Shimoda+N%22">Shimoda N</searchLink>; Functional Genomics Unit, Medical Genome Center, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Kasuga+K%22">Kasuga K</searchLink>; Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.<br /><searchLink fieldCode="AU" term="%22Ikeuchi+T%22">Ikeuchi T</searchLink>; Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.<br /><searchLink fieldCode="AU" term="%22Takeda+A%22">Takeda A</searchLink>; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Sakurai+T%22">Sakurai T</searchLink>; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+K%22">Ito K</searchLink>; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+T%22">Kato T</searchLink>; National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan.
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