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Transcriptomic profiling of pancreatic neuroendocrine tumors: dysregulation of WNT, MAPK, PI3K, neddylation pathways and potential non-invasive biomarkers.

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Title: Transcriptomic profiling of pancreatic neuroendocrine tumors: dysregulation of WNT, MAPK, PI3K, neddylation pathways and potential non-invasive biomarkers.
Authors: Niedra H; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia., Rogoza O; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia., Saksis R; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia., Peculis R; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia., Halilova A; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia., Gerina A; Pauls Stradins Clinical University Hospital, Pilsonu Str, Riga, Latvia., Vilisova S; Pauls Stradins Clinical University Hospital, Pilsonu Str, Riga, Latvia., Senterjakova N; Pauls Stradins Clinical University Hospital, Pilsonu Str, Riga, Latvia., Pukitis A; Pauls Stradins Clinical University Hospital, Pilsonu Str, Riga, Latvia., Ruz-Caracuel I; Department of Pathology, Ramón y Cajal University Hospital, Ctra. Colmenar Viejo, Madrid, Spain., Earl J; Ramón y Cajal Health Research Institute (IRYCIS), Ramón y Cajal University Hospital, Ctra. Colmenar Viejo, Madrid, CIBERONC, Spain., Kolnikova G; Department of Pathology, National Cancer Institute, Klenová, Bratislava, Slovak Republic., Dubovan P; Department of Surgical Oncology of Slovak Medical University in Bratislava, National Cancer Institute, Klenová, Bratislava, Slovak Republic.; Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta, Bratislava, Slovak Republic., Tomas M; Department of Surgical Oncology of Slovak Medical University in Bratislava, National Cancer Institute, Klenová, Bratislava, Slovak Republic.; Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta, Bratislava, Slovak Republic., Makovicky P; Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta, Bratislava, Slovak Republic., Urbanova M; Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta, Bratislava, Slovak Republic., Smolkova B; Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta, Bratislava, Slovak Republic., Koniaris E; Department of Pathology, Hippokration General Hospital of Athens, Vasilissis Sofias, Athens, Greece., Aggelioudaki I; Second Department of Surgery, Aretaieio University Hospital, Vasilissis Sofias, Athens, Greece., Kataki A; First Department of Propaedeutic Surgery, Hippokration General Hospital of Athens, Vasilissis Sofias, Athens, Greece., Rovite V; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia.
Source: PloS one [PLoS One] 2025 Jun 16; Vol. 20 (6), pp. e0325672. Date of Electronic Publication: 2025 Jun 16 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Transcriptomic profiling of pancreatic neuroendocrine tumors: dysregulation of WNT, MAPK, PI3K, neddylation pathways and potential non-invasive biomarkers.
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  Data: <searchLink fieldCode="AU" term="%22Niedra+H%22">Niedra H</searchLink>; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Rogoza+O%22">Rogoza O</searchLink>; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Saksis+R%22">Saksis R</searchLink>; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Peculis+R%22">Peculis R</searchLink>; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Halilova+A%22">Halilova A</searchLink>; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Gerina+A%22">Gerina A</searchLink>; Pauls Stradins Clinical University Hospital, Pilsonu Str, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Vilisova+S%22">Vilisova S</searchLink>; Pauls Stradins Clinical University Hospital, Pilsonu Str, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Senterjakova+N%22">Senterjakova N</searchLink>; Pauls Stradins Clinical University Hospital, Pilsonu Str, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Pukitis+A%22">Pukitis A</searchLink>; Pauls Stradins Clinical University Hospital, Pilsonu Str, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Ruz-Caracuel+I%22">Ruz-Caracuel I</searchLink>; Department of Pathology, Ramón y Cajal University Hospital, Ctra. Colmenar Viejo, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Earl+J%22">Earl J</searchLink>; Ramón y Cajal Health Research Institute (IRYCIS), Ramón y Cajal University Hospital, Ctra. Colmenar Viejo, Madrid, CIBERONC, Spain.<br /><searchLink fieldCode="AU" term="%22Kolnikova+G%22">Kolnikova G</searchLink>; Department of Pathology, National Cancer Institute, Klenová, Bratislava, Slovak Republic.<br /><searchLink fieldCode="AU" term="%22Dubovan+P%22">Dubovan P</searchLink>; Department of Surgical Oncology of Slovak Medical University in Bratislava, National Cancer Institute, Klenová, Bratislava, Slovak Republic.; Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta, Bratislava, Slovak Republic.<br /><searchLink fieldCode="AU" term="%22Tomas+M%22">Tomas M</searchLink>; Department of Surgical Oncology of Slovak Medical University in Bratislava, National Cancer Institute, Klenová, Bratislava, Slovak Republic.; Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta, Bratislava, Slovak Republic.<br /><searchLink fieldCode="AU" term="%22Makovicky+P%22">Makovicky P</searchLink>; Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta, Bratislava, Slovak Republic.<br /><searchLink fieldCode="AU" term="%22Urbanova+M%22">Urbanova M</searchLink>; Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta, Bratislava, Slovak Republic.<br /><searchLink fieldCode="AU" term="%22Smolkova+B%22">Smolkova B</searchLink>; Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta, Bratislava, Slovak Republic.<br /><searchLink fieldCode="AU" term="%22Koniaris+E%22">Koniaris E</searchLink>; Department of Pathology, Hippokration General Hospital of Athens, Vasilissis Sofias, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Aggelioudaki+I%22">Aggelioudaki I</searchLink>; Second Department of Surgery, Aretaieio University Hospital, Vasilissis Sofias, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Kataki+A%22">Kataki A</searchLink>; First Department of Propaedeutic Surgery, Hippokration General Hospital of Athens, Vasilissis Sofias, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Rovite+V%22">Rovite V</searchLink>; Latvian Biomedical Research and Study Centre, Ratsupites Str, Riga, Latvia.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2025 Jun 16; Vol. 20 (6), pp. e0325672. <i>Date of Electronic Publication: </i>2025 Jun 16 (<i>Print Publication: </i>2025).
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