Unraveling the Role of THRIL/miR-137 in Fine-Tuning the Immunological Transcriptional Loop STAT4/STAT6/GATA3 in Multiple Sclerosis: Implications on Neurological Complications and Disease Subtypes.

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Title: Unraveling the Role of THRIL/miR-137 in Fine-Tuning the Immunological Transcriptional Loop STAT4/STAT6/GATA3 in Multiple Sclerosis: Implications on Neurological Complications and Disease Subtypes.
Authors: Ayeldeen G; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Giza 12613, Egypt., Badr BM; Department of Basic and Clinical Medical Sciences, Faculty of Dentistry, Zarqa University, Zarqa 132222, Jordan.; Department of Medical Microbiology and Immunology, Faculty of Medicine, Al-Azhar University, Cairo 11651, Egypt., Awaji AA; Department of Biology, Faculty of Science, University College of Taymaa, University of Tabuk, Tabuk 71491, Saudi Arabia., Gaber DA; Medical Biochemistry & Molecular Biology Department, Faculty of Medicine, Helwan University, Cairo 11795, Egypt.; College of Medicine, Gulf Medical University, Ajman 4184, United Arab Emirates., Elelwany DA; Department of Neurology, Faculty of Medicine, Cairo University, Giza 12613, Egypt., Al Abdulqader AK; Department of Internal Medicine, College of Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia., Shaker OG; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Giza 12613, Egypt., Abd-Elmawla MA; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Source: ACS chemical neuroscience [ACS Chem Neurosci] 2025 Jul 02; Vol. 16 (13), pp. 2513-2527. Date of Electronic Publication: 2025 Jun 16.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Ayeldeen+G%22">Ayeldeen G</searchLink>; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Giza 12613, Egypt.<br /><searchLink fieldCode="AU" term="%22Badr+BM%22">Badr BM</searchLink>; Department of Basic and Clinical Medical Sciences, Faculty of Dentistry, Zarqa University, Zarqa 132222, Jordan.; Department of Medical Microbiology and Immunology, Faculty of Medicine, Al-Azhar University, Cairo 11651, Egypt.<br /><searchLink fieldCode="AU" term="%22Awaji+AA%22">Awaji AA</searchLink>; Department of Biology, Faculty of Science, University College of Taymaa, University of Tabuk, Tabuk 71491, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Gaber+DA%22">Gaber DA</searchLink>; Medical Biochemistry & Molecular Biology Department, Faculty of Medicine, Helwan University, Cairo 11795, Egypt.; College of Medicine, Gulf Medical University, Ajman 4184, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Elelwany+DA%22">Elelwany DA</searchLink>; Department of Neurology, Faculty of Medicine, Cairo University, Giza 12613, Egypt.<br /><searchLink fieldCode="AU" term="%22Al+Abdulqader+AK%22">Al Abdulqader AK</searchLink>; Department of Internal Medicine, College of Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Shaker+OG%22">Shaker OG</searchLink>; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Giza 12613, Egypt.<br /><searchLink fieldCode="AU" term="%22Abd-Elmawla+MA%22">Abd-Elmawla MA</searchLink>; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
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        Value: 10.1021/acschemneuro.5c00299
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      – TitleFull: Unraveling the Role of THRIL/miR-137 in Fine-Tuning the Immunological Transcriptional Loop STAT4/STAT6/GATA3 in Multiple Sclerosis: Implications on Neurological Complications and Disease Subtypes.
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              Text: 2025 Jul 02
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