Epac1 increases myosin regulatory light-chain phosphorylation, energetic cost of contraction, and susceptibility to heart failure. - Ohnuki Y; Suita K; Ishikawa M; Mototani Y; Nariyama M; Ito A; Matsuo I; Hayakawa Y; Morii A; Mitsubayashi T; Saeki Y; Ishikawa Y; et al. (PloS one, 2025)