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Novel PI3kδ inhibitor roginolisib synergizes with venetoclax in hematologic malignancies.

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Title: Novel PI3kδ inhibitor roginolisib synergizes with venetoclax in hematologic malignancies.
Authors: Sasi BK; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts., Tarantelli C; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona., Martindale S; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts., Civanelli E; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona., Cannas E; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona., Sartori G; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona., Arribas AJ; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona., Fernandes SM; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts., Shupe SJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts., Machado JH; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts., Tyekucheva S; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Ren Y; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Lahn M; iOnctura SA; Geneva., Van der Veen L; iOnctura BV; Amsterdam, Netherlands., Di Conza G; iOnctura SA; Geneva., Bertoni F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona, Switzerland; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale; Bellinzona. francesco.bertoni@ior.usi.ch., Brown JR; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts, USA; Chronic Lymphocytic Leukemia Center, Division of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School; Boston, MA. jennifer_brown@dfci.harvard.edu.
Source: Haematologica [Haematologica] 2025 Dec 01; Vol. 110 (12), pp. 2974-2985. Date of Electronic Publication: 2025 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel PI3kδ inhibitor roginolisib synergizes with venetoclax in hematologic malignancies.
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  Data: <searchLink fieldCode="AU" term="%22Sasi+BK%22">Sasi BK</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Tarantelli+C%22">Tarantelli C</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona.<br /><searchLink fieldCode="AU" term="%22Martindale+S%22">Martindale S</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Civanelli+E%22">Civanelli E</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona.<br /><searchLink fieldCode="AU" term="%22Cannas+E%22">Cannas E</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona.<br /><searchLink fieldCode="AU" term="%22Sartori+G%22">Sartori G</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona.<br /><searchLink fieldCode="AU" term="%22Arribas+AJ%22">Arribas AJ</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona.<br /><searchLink fieldCode="AU" term="%22Fernandes+SM%22">Fernandes SM</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Shupe+SJ%22">Shupe SJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Machado+JH%22">Machado JH</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Tyekucheva+S%22">Tyekucheva S</searchLink>; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Ren+Y%22">Ren Y</searchLink>; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Lahn+M%22">Lahn M</searchLink>; iOnctura SA; Geneva.<br /><searchLink fieldCode="AU" term="%22Van+der+Veen+L%22">Van der Veen L</searchLink>; iOnctura BV; Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Di+Conza+G%22">Di Conza G</searchLink>; iOnctura SA; Geneva.<br /><searchLink fieldCode="AU" term="%22Bertoni+F%22">Bertoni F</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI; Bellinzona, Switzerland; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale; Bellinzona. francesco.bertoni@ior.usi.ch.<br /><searchLink fieldCode="AU" term="%22Brown+JR%22">Brown JR</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts, USA; Chronic Lymphocytic Leukemia Center, Division of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School; Boston, MA. jennifer_brown@dfci.harvard.edu.
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  Data: <searchLink fieldCode="JN" term="%220417435%22">Haematologica</searchLink> [Haematologica] 2025 Dec 01; Vol. 110 (12), pp. 2974-2985. <i>Date of Electronic Publication: </i>2025 Jun 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ferrata+Storti+Foundation%22">Ferrata Storti Foundation </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>0417435 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1592-8721 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203906078%22">03906078 </searchLink><i>NLM ISO Abbreviation: </i>Haematologica <i>Subsets: </i>MEDLINE
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        Value: 10.3324/haematol.2024.287180
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              Text: 2025 Dec 01
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