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The olfactory epithelium: a critical gateway for pathological tau propagation and a target for mitigating tauopathy in the central nervous system.

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Title: The olfactory epithelium: a critical gateway for pathological tau propagation and a target for mitigating tauopathy in the central nervous system.
Authors: Dourte M; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium., Paître E; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium., Bouchoucha M; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium., Boyer E; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium., Tomé SO; Laboratory for Neuropathology, Department of Imaging and Pathology, Leuven Brain Institute (LBI), KU Leuven, Leuven, Belgium., Doeraene E; Alzheimer and Other Tauopathies Research Group, ULB Neuroscience Institute (UNI), ULB Center for Diabetes Research (UCDR), Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium., Huart C; OlfactIoNS Group, Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium.; Department of Otorhinolaryngology, Head and Neck Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Leroy K; Alzheimer and Other Tauopathies Research Group, ULB Neuroscience Institute (UNI), ULB Center for Diabetes Research (UCDR), Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium., Thal DR; Laboratory for Neuropathology, Department of Imaging and Pathology, Leuven Brain Institute (LBI), KU Leuven, Leuven, Belgium.; Department of Pathology, University Hospital Leuven, Leuven, Belgium., Decottignies A; Genetic and Epigenetic Alterations of Genomes Unit, de Duve Institute, UCLouvain, Brussels, Belgium., Hanseeuw B; Louvain Aging Lab, Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium.; Neurology Department, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Suelves N; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium., Kienlen-Campard P; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium. pascal.kienlen-campard@uclouvain.be.
Source: Acta neuropathologica [Acta Neuropathol] 2025 Jun 19; Vol. 149 (1), pp. 64. Date of Electronic Publication: 2025 Jun 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The olfactory epithelium: a critical gateway for pathological tau propagation and a target for mitigating tauopathy in the central nervous system.
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  Data: <searchLink fieldCode="AU" term="%22Dourte+M%22">Dourte M</searchLink>; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Paître+E%22">Paître E</searchLink>; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Bouchoucha+M%22">Bouchoucha M</searchLink>; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Boyer+E%22">Boyer E</searchLink>; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Tomé+SO%22">Tomé SO</searchLink>; Laboratory for Neuropathology, Department of Imaging and Pathology, Leuven Brain Institute (LBI), KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Doeraene+E%22">Doeraene E</searchLink>; Alzheimer and Other Tauopathies Research Group, ULB Neuroscience Institute (UNI), ULB Center for Diabetes Research (UCDR), Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Huart+C%22">Huart C</searchLink>; OlfactIoNS Group, Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium.; Department of Otorhinolaryngology, Head and Neck Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Leroy+K%22">Leroy K</searchLink>; Alzheimer and Other Tauopathies Research Group, ULB Neuroscience Institute (UNI), ULB Center for Diabetes Research (UCDR), Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Thal+DR%22">Thal DR</searchLink>; Laboratory for Neuropathology, Department of Imaging and Pathology, Leuven Brain Institute (LBI), KU Leuven, Leuven, Belgium.; Department of Pathology, University Hospital Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Decottignies+A%22">Decottignies A</searchLink>; Genetic and Epigenetic Alterations of Genomes Unit, de Duve Institute, UCLouvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Hanseeuw+B%22">Hanseeuw B</searchLink>; Louvain Aging Lab, Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium.; Neurology Department, Cliniques Universitaires Saint-Luc, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Suelves+N%22">Suelves N</searchLink>; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Kienlen-Campard+P%22">Kienlen-Campard P</searchLink>; Aging and Dementia Group, Cellular and Molecular Division (CEMO), Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium. pascal.kienlen-campard@uclouvain.be.
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  Data: <searchLink fieldCode="JN" term="%220412041%22">Acta neuropathologica</searchLink> [Acta Neuropathol] 2025 Jun 19; Vol. 149 (1), pp. 64. <i>Date of Electronic Publication: </i>2025 Jun 19.
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