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Timing of Changes in Alzheimer's Disease Plasma Biomarkers as Assessed by Amyloid and Tau PET Clocks.

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Title: Timing of Changes in Alzheimer's Disease Plasma Biomarkers as Assessed by Amyloid and Tau PET Clocks.
Authors: Milà-Alomà M; Northern California Institute for Research and Education, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA., Tosun D; Northern California Institute for Research and Education, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA., Schindler SE; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Hausle I; Northern California Institute for Research and Education, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA., Petersen KK; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Li Y; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Dage JL; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Du-Cuny L; AbbVie, Ludwigshafen am Rhein, Rheinland-Pfalz, Germany., Saad ZS; Neuroscience Biomarkers, Johnson and Johnson Innovative Medicine, San Diego, CA, USA., Saef B; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Triana-Baltzer G; Neuroscience Biomarkers, Johnson and Johnson Innovative Medicine, San Diego, CA, USA., Raunig DL; Takeda Pharmaceutical Company Ltd., Cambridge, MA, USA., Coomaraswamy J; Takeda Pharmaceutical Company Ltd., Cambridge, MA, USA., Baratta M; Takeda Pharmaceutical Company Ltd., Cambridge, MA, USA., Meyers EA; Alzheimer's Association, Chicago, IL, USA., Mordashova Y; AbbVie, Ludwigshafen am Rhein, Rheinland-Pfalz, Germany., Rubel CE; Biogen, Cambridge, MA, USA., Ferber K; Biogen, Cambridge, MA, USA., Kolb H; Enigma Biomedical Group, San Diego, CA, USA., Ashton NJ; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden., Zetterberg H; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; UK Dementia Research Institute Fluid Biomarkers Laboratory, UK DRI at UCL, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Rosenbaugh EG; The Foundation for the National Institutes of Health, North Bethesda, MD, USA., Sabandal M; The Foundation for the National Institutes of Health, North Bethesda, MD, USA., Shaw LM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Bannon AW; AbbVie, North Chicago, IL, USA., Potter WZ
Corporate Authors: Alzheimer's Disease Neuroimaging Initiative (ADNI), Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium Plasma Aβ and Phosphorylated Tau as Predictors of Amyloid and Tau Positivity in Alzheimer's Disease Project Team
Source: Annals of neurology [Ann Neurol] 2025 Sep; Vol. 98 (3), pp. 508-523. Date of Electronic Publication: 2025 Jun 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7707449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8249 (Electronic) Linking ISSN: 03645134 NLM ISO Abbreviation: Ann Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Timing of Changes in Alzheimer's Disease Plasma Biomarkers as Assessed by Amyloid and Tau PET Clocks.
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  Data: <searchLink fieldCode="AU" term="%22Milà-Alomà+M%22">Milà-Alomà M</searchLink>; Northern California Institute for Research and Education, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tosun+D%22">Tosun D</searchLink>; Northern California Institute for Research and Education, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Schindler+SE%22">Schindler SE</searchLink>; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Hausle+I%22">Hausle I</searchLink>; Northern California Institute for Research and Education, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Petersen+KK%22">Petersen KK</searchLink>; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Dage+JL%22">Dage JL</searchLink>; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Du-Cuny+L%22">Du-Cuny L</searchLink>; AbbVie, Ludwigshafen am Rhein, Rheinland-Pfalz, Germany.<br /><searchLink fieldCode="AU" term="%22Saad+ZS%22">Saad ZS</searchLink>; Neuroscience Biomarkers, Johnson and Johnson Innovative Medicine, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Saef+B%22">Saef B</searchLink>; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Triana-Baltzer+G%22">Triana-Baltzer G</searchLink>; Neuroscience Biomarkers, Johnson and Johnson Innovative Medicine, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Raunig+DL%22">Raunig DL</searchLink>; Takeda Pharmaceutical Company Ltd., Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Coomaraswamy+J%22">Coomaraswamy J</searchLink>; Takeda Pharmaceutical Company Ltd., Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Baratta+M%22">Baratta M</searchLink>; Takeda Pharmaceutical Company Ltd., Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Meyers+EA%22">Meyers EA</searchLink>; Alzheimer's Association, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Mordashova+Y%22">Mordashova Y</searchLink>; AbbVie, Ludwigshafen am Rhein, Rheinland-Pfalz, Germany.<br /><searchLink fieldCode="AU" term="%22Rubel+CE%22">Rubel CE</searchLink>; Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ferber+K%22">Ferber K</searchLink>; Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kolb+H%22">Kolb H</searchLink>; Enigma Biomedical Group, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ashton+NJ%22">Ashton NJ</searchLink>; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; UK Dementia Research Institute Fluid Biomarkers Laboratory, UK DRI at UCL, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Rosenbaugh+EG%22">Rosenbaugh EG</searchLink>; The Foundation for the National Institutes of Health, North Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sabandal+M%22">Sabandal M</searchLink>; The Foundation for the National Institutes of Health, North Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Shaw+LM%22">Shaw LM</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bannon+AW%22">Bannon AW</searchLink>; AbbVie, North Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Potter+WZ%22">Potter WZ</searchLink>
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  Data: <searchLink fieldCode="CA" term="%22Alzheimer's+Disease+Neuroimaging+Initiative+%28ADNI%29%22">Alzheimer's Disease Neuroimaging Initiative (ADNI)</searchLink><br /><searchLink fieldCode="CA" term="%22Foundation+for+the+National+Institutes+of+Health+%28FNIH%29+Biomarkers+Consortium+Plasma+Aβ+and+Phosphorylated+Tau+as+Predictors+of+Amyloid+and+Tau+Positivity+in+Alzheimer's+Disease+Project+Team%22">Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium Plasma Aβ and Phosphorylated Tau as Predictors of Amyloid and Tau Positivity in Alzheimer's Disease Project Team</searchLink>
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  Data: <searchLink fieldCode="JN" term="%227707449%22">Annals of neurology</searchLink> [Ann Neurol] 2025 Sep; Vol. 98 (3), pp. 508-523. <i>Date of Electronic Publication: </i>2025 Jun 20.
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