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Characterization of the tautomeric equilibrium of molnupiravir, an antiviral for the treatment of COVID-19.

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Title: Characterization of the tautomeric equilibrium of molnupiravir, an antiviral for the treatment of COVID-19.
Authors: Burgess SA; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA. Electronic address: samantha.burgess@merck.com., Wang X; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA., Stueber D; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA., Wang Y; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA., Cohen RD; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA., Lam YH; Modeling & Informatics, Discovery Chemistry, Merck & Co., Inc., Rahway, NJ 07065, USA., Iuzzolino L; Modeling & Informatics, Discovery Chemistry, Merck & Co., Inc., Rahway, NJ 07065, USA., Reibarkh M; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA. Electronic address: mikhail_reibarkh@merck.com.
Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2025 Nov 15; Vol. 265, pp. 117025. Date of Electronic Publication: 2025 Jun 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Burgess+SA%22">Burgess SA</searchLink>; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA. Electronic address: samantha.burgess@merck.com.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA.<br /><searchLink fieldCode="AU" term="%22Stueber+D%22">Stueber D</searchLink>; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+RD%22">Cohen RD</searchLink>; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA.<br /><searchLink fieldCode="AU" term="%22Lam+YH%22">Lam YH</searchLink>; Modeling & Informatics, Discovery Chemistry, Merck & Co., Inc., Rahway, NJ 07065, USA.<br /><searchLink fieldCode="AU" term="%22Iuzzolino+L%22">Iuzzolino L</searchLink>; Modeling & Informatics, Discovery Chemistry, Merck & Co., Inc., Rahway, NJ 07065, USA.<br /><searchLink fieldCode="AU" term="%22Reibarkh+M%22">Reibarkh M</searchLink>; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ 07065, USA. Electronic address: mikhail_reibarkh@merck.com.
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              Text: 2025 Nov 15
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