Cryogenic mouse tissue homogenization as an alternative to fresh-frozen biopsy use for genomics, transcriptomics, proteomics and metabolomics.
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| Title: | Cryogenic mouse tissue homogenization as an alternative to fresh-frozen biopsy use for genomics, transcriptomics, proteomics and metabolomics. |
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| Authors: | Zizmare L; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University of Tübingen, 72076, Tübingen, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, 72076, Tübingen, Germany., Hofmann U; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, University of Tübingen, 70376, Stuttgart, Germany., Jarboui MA; Core Facility for Medical Proteomics, Institute for Ophthalmic Research, University of Tübingen, 72076, Tübingen, Germany., Klose F; Core Facility for Medical Proteomics, Institute for Ophthalmic Research, University of Tübingen, 72076, Tübingen, Germany., Fraschka S; NGS Competence Center Tübingen (NCCT), Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076, Tübingen, Germany.; Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076, Tübingen, Germany., Matthes J; NGS Competence Center Tübingen (NCCT), Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076, Tübingen, Germany.; Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076, Tübingen, Germany., Krüger M; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University of Tübingen, 72076, Tübingen, Germany., Schaeffeler E; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, 72076, Tübingen, Germany.; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, University of Tübingen, 70376, Stuttgart, Germany., Schwab M; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, 72076, Tübingen, Germany.; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, University of Tübingen, 70376, Stuttgart, Germany.; Department of Clinical Pharmacology, and Department of Biochemistry and Pharmacy, University of Tübingen, 72076, Tübingen, Germany., Ueffing M; Core Facility for Medical Proteomics, Institute for Ophthalmic Research, University of Tübingen, 72076, Tübingen, Germany., Pichler BJ; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University of Tübingen, 72076, Tübingen, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, 72076, Tübingen, Germany., Boldt K; Core Facility for Medical Proteomics, Institute for Ophthalmic Research, University of Tübingen, 72076, Tübingen, Germany., Casadei N; NGS Competence Center Tübingen (NCCT), Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076, Tübingen, Germany.; Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076, Tübingen, Germany., Trautwein C; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University of Tübingen, 72076, Tübingen, Germany. Christoph.Trautwein@med.uni-tuebingen.de.; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, 72076, Tübingen, Germany. Christoph.Trautwein@med.uni-tuebingen.de.; Core Facility Metabolomics, Faculty of Medicine, University of Tübingen, 72076, Tübingen, Germany. Christoph.Trautwein@med.uni-tuebingen.de. |
| Source: | Scientific reports [Sci Rep] 2025 Jun 23; Vol. 15 (1), pp. 20254. Date of Electronic Publication: 2025 Jun 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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