Facile and Practical Synthesis of Substituted Piperidine-2,6-Diones Under Transition-Metal Free Condition.

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Title: Facile and Practical Synthesis of Substituted Piperidine-2,6-Diones Under Transition-Metal Free Condition.
Authors: Liu YH; School of Pharmaceutical Sciences and Institute of Materia Medical, National Key Laboratory of Advanced Drug Delivery System, Key Laboratory for Biotechnology Drugs of National Health Commission (Shandong Academy of Medical Sciences), Key Lab for Rare and Uncommon Diseases of Shandong Province, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China., Xue ZQ; School of Pharmaceutical Sciences and Institute of Materia Medical, National Key Laboratory of Advanced Drug Delivery System, Key Laboratory for Biotechnology Drugs of National Health Commission (Shandong Academy of Medical Sciences), Key Lab for Rare and Uncommon Diseases of Shandong Province, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China., Yang KW; School of Pharmaceutical Sciences and Institute of Materia Medical, National Key Laboratory of Advanced Drug Delivery System, Key Laboratory for Biotechnology Drugs of National Health Commission (Shandong Academy of Medical Sciences), Key Lab for Rare and Uncommon Diseases of Shandong Province, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China., Yin HW; School of Pharmaceutical Sciences and Institute of Materia Medical, National Key Laboratory of Advanced Drug Delivery System, Key Laboratory for Biotechnology Drugs of National Health Commission (Shandong Academy of Medical Sciences), Key Lab for Rare and Uncommon Diseases of Shandong Province, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China., Yang B; Department School of Chemical Engineering and Food Science, Hubei University of Arts and Science, 296 Longzhong Road, Xiangyang, 441053, Hubei, P. R. China., Zhang R; Hubei Key Laboratory of Low Dimensional Optoelectronic Material and Devices, Hubei University of Arts and Science, 296 Longzhong Road, Xiangyang, 441053, Hubei, P. R. China.; Department School of Chemical Engineering and Food Science, Hubei University of Arts and Science, 296 Longzhong Road, Xiangyang, 441053, Hubei, P. R. China., Zhong H; Medical Science and Technology Innovation Center (Institute of Translational Medicine), Shandong First Medical University and Shandong Academy of Medical Sciences), Jinan, 250117, Shandong, China., Bai ZS; School of Pharmaceutical Sciences and Institute of Materia Medical, National Key Laboratory of Advanced Drug Delivery System, Key Laboratory for Biotechnology Drugs of National Health Commission (Shandong Academy of Medical Sciences), Key Lab for Rare and Uncommon Diseases of Shandong Province, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China.
Source: ChemistryOpen [ChemistryOpen] 2025 Nov; Vol. 14 (11), pp. e202500067. Date of Electronic Publication: 2025 Jun 27.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101594811 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2191-1363 (Electronic) Linking ISSN: 21911363 NLM ISO Abbreviation: ChemistryOpen Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2191-1363
DOI:10.1002/open.202500067