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Critical impact of lysine 136 in TDP-43 phase separation, compartmentalization, and aggregation in living vertebrates.

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Title: Critical impact of lysine 136 in TDP-43 phase separation, compartmentalization, and aggregation in living vertebrates.
Authors: Maurel C; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Scherer NM; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Luu L; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Radford RA; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Hogan A; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Merjane J; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia., Vidal-Itriago A; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Don EK; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Chapman T; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Cull S; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Vourc'h P; Service de Biochimie et Biologie Moléculaire, Centre Hospitalier Universitaire de Tours, Tours 1253, France, UMR 1253, iBRAIN, Université de Tours, INSERM, Tours, France., Lisowski L; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.; Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine - National Research Institute, 04-141 Warsaw, Poland., Lee A; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Chung RS; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Morsch M; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.
Source: IScience [iScience] 2025 May 27; Vol. 28 (7), pp. 112761. Date of Electronic Publication: 2025 May 27 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Maurel+C%22">Maurel C</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Scherer+NM%22">Scherer NM</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Luu+L%22">Luu L</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Radford+RA%22">Radford RA</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Hogan+A%22">Hogan A</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Merjane+J%22">Merjane J</searchLink>; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.<br /><searchLink fieldCode="AU" term="%22Vidal-Itriago+A%22">Vidal-Itriago A</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Don+EK%22">Don EK</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Chapman+T%22">Chapman T</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Cull+S%22">Cull S</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Vourc'h+P%22">Vourc'h P</searchLink>; Service de Biochimie et Biologie Moléculaire, Centre Hospitalier Universitaire de Tours, Tours 1253, France, UMR 1253, iBRAIN, Université de Tours, INSERM, Tours, France.<br /><searchLink fieldCode="AU" term="%22Lisowski+L%22">Lisowski L</searchLink>; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.; Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine - National Research Institute, 04-141 Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Lee+A%22">Lee A</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Chung+RS%22">Chung RS</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Morsch+M%22">Morsch M</searchLink>; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.
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