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Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants.

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Title: Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants.
Authors: Förster F; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany. franz.foerster@imise.uni-leipzig.de.; Institute of Molecular Biology gGmbH (IMB), Mainz, Germany. franz.foerster@imise.uni-leipzig.de., Emmert D; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Horn K; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany., Pott J; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany.; University of Cambridge, MRC Biostatistics Unit, Cambridge, United Kingdom., Frasnelli J; Institute for Biomedicine, Eurac Research, Bolzano, Italy.; Department of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada., Imtiaz MA; German Centre for Neurodegenerative Diseases (DZNE), Population Health Sciences, Bonn, Germany., Melas K; German Centre for Neurodegenerative Diseases (DZNE), Population Health Sciences, Bonn, Germany., Talevi V; German Centre for Neurodegenerative Diseases (DZNE), Population Health Sciences, Bonn, Germany., Chen H; Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA., Engel C; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, Medical Faculty, Leipzig University, Leipzig, Germany., Filosi M; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science at Houston, Houston, TX, USA.; Human Genetics Center, School of Public Health, University of Texas Health Science at Houston, Houston, TX, USA., Gögele M; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Löffler M; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, Medical Faculty, Leipzig University, Leipzig, Germany., Mosley TH; The Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA., Pattaro C; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Pramstaller P; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Shrestha S; The Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA., Aziz NA; German Centre for Neurodegenerative Diseases (DZNE), Population Health Sciences, Bonn, Germany.; Department of Neurology, Faculty of Medicine, University of Bonn, Bonn, Germany., Breteler MMB; German Centre for Neurodegenerative Diseases (DZNE), Population Health Sciences, Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), Faculty of Medicine, University of Bonn, Bonn, Germany., Wirkner K; LIFE - Leipzig Research Centre for Civilization Diseases, Medical Faculty, Leipzig University, Leipzig, Germany., Scholz M; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany. markus.scholz@imise.uni-leipzig.de.; LIFE - Leipzig Research Centre for Civilization Diseases, Medical Faculty, Leipzig University, Leipzig, Germany. markus.scholz@imise.uni-leipzig.de., Fuchsberger C; Institute for Biomedicine, Eurac Research, Bolzano, Italy. Christian.Fuchsberger@eurac.edu.
Source: Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5434. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants.
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  Data: <searchLink fieldCode="AU" term="%22Förster+F%22">Förster F</searchLink>; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany. franz.foerster@imise.uni-leipzig.de.; Institute of Molecular Biology gGmbH (IMB), Mainz, Germany. franz.foerster@imise.uni-leipzig.de.<br /><searchLink fieldCode="AU" term="%22Emmert+D%22">Emmert D</searchLink>; Institute for Biomedicine, Eurac Research, Bolzano, Italy.<br /><searchLink fieldCode="AU" term="%22Horn+K%22">Horn K</searchLink>; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Pott+J%22">Pott J</searchLink>; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany.; University of Cambridge, MRC Biostatistics Unit, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Frasnelli+J%22">Frasnelli J</searchLink>; Institute for Biomedicine, Eurac Research, Bolzano, Italy.; Department of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Imtiaz+MA%22">Imtiaz MA</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Population Health Sciences, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Melas+K%22">Melas K</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Population Health Sciences, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Talevi+V%22">Talevi V</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Population Health Sciences, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.<br /><searchLink fieldCode="AU" term="%22Engel+C%22">Engel C</searchLink>; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, Medical Faculty, Leipzig University, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Filosi+M%22">Filosi M</searchLink>; Institute for Biomedicine, Eurac Research, Bolzano, Italy.<br /><searchLink fieldCode="AU" term="%22Fornage+M%22">Fornage M</searchLink>; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science at Houston, Houston, TX, USA.; Human Genetics Center, School of Public Health, University of Texas Health Science at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Gögele+M%22">Gögele M</searchLink>; Institute for Biomedicine, Eurac Research, Bolzano, Italy.<br /><searchLink fieldCode="AU" term="%22Löffler+M%22">Löffler M</searchLink>; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, Medical Faculty, Leipzig University, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Mosley+TH%22">Mosley TH</searchLink>; The Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA.<br /><searchLink fieldCode="AU" term="%22Pattaro+C%22">Pattaro C</searchLink>; Institute for Biomedicine, Eurac Research, Bolzano, Italy.<br /><searchLink fieldCode="AU" term="%22Pramstaller+P%22">Pramstaller P</searchLink>; Institute for Biomedicine, Eurac Research, Bolzano, Italy.<br /><searchLink fieldCode="AU" term="%22Shrestha+S%22">Shrestha S</searchLink>; The Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA.<br /><searchLink fieldCode="AU" term="%22Aziz+NA%22">Aziz NA</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Population Health Sciences, Bonn, Germany.; Department of Neurology, Faculty of Medicine, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Breteler+MMB%22">Breteler MMB</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Population Health Sciences, Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), Faculty of Medicine, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Wirkner+K%22">Wirkner K</searchLink>; LIFE - Leipzig Research Centre for Civilization Diseases, Medical Faculty, Leipzig University, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Scholz+M%22">Scholz M</searchLink>; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Medical Faculty, Leipzig University, Leipzig, Germany. markus.scholz@imise.uni-leipzig.de.; LIFE - Leipzig Research Centre for Civilization Diseases, Medical Faculty, Leipzig University, Leipzig, Germany. markus.scholz@imise.uni-leipzig.de.<br /><searchLink fieldCode="AU" term="%22Fuchsberger+C%22">Fuchsberger C</searchLink>; Institute for Biomedicine, Eurac Research, Bolzano, Italy. Christian.Fuchsberger@eurac.edu.
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