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Esketamine Monotherapy in Adults With Treatment-Resistant Depression: A Randomized Clinical Trial.

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Title: Esketamine Monotherapy in Adults With Treatment-Resistant Depression: A Randomized Clinical Trial.
Authors: Janik A; Department of Neuroscience, Johnson & Johnson, San Diego, California., Qiu X; Department of Clinical Biostatistics, Johnson & Johnson, Titusville, New Jersey., Lane R; Department of Clinical Biostatistics, Johnson & Johnson, Titusville, New Jersey., Popova V; Department of Neuroscience, Johnson & Johnson, Beerse, Belgium., Drevets WC; Department of Neuroscience, Johnson & Johnson, San Diego, California., Canuso CM; Department of Neuroscience, Johnson & Johnson, Titusville, New Jersey., Macaluso M; Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham., Mattingly GW; Midwest Research Group-St Charles Psychiatric Associates, St Charles, Missouri., Shelton RC; Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham School of Medicine, Huntsville Regional Medical Campus, Huntsville., Zajecka JM; Department of Psychiatry, Rush University, Chicago, Illinois., Fu DJ; Department of Neuroscience, Johnson & Johnson, Titusville, New Jersey.
Source: JAMA psychiatry [JAMA Psychiatry] 2025 Sep 01; Vol. 82 (9), pp. 877-887.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase IV
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589550 Publication Model: Print Cited Medium: Internet ISSN: 2168-6238 (Electronic) Linking ISSN: 2168622X NLM ISO Abbreviation: JAMA Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Janik+A%22">Janik A</searchLink>; Department of Neuroscience, Johnson & Johnson, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Qiu+X%22">Qiu X</searchLink>; Department of Clinical Biostatistics, Johnson & Johnson, Titusville, New Jersey.<br /><searchLink fieldCode="AU" term="%22Lane+R%22">Lane R</searchLink>; Department of Clinical Biostatistics, Johnson & Johnson, Titusville, New Jersey.<br /><searchLink fieldCode="AU" term="%22Popova+V%22">Popova V</searchLink>; Department of Neuroscience, Johnson & Johnson, Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Drevets+WC%22">Drevets WC</searchLink>; Department of Neuroscience, Johnson & Johnson, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Canuso+CM%22">Canuso CM</searchLink>; Department of Neuroscience, Johnson & Johnson, Titusville, New Jersey.<br /><searchLink fieldCode="AU" term="%22Macaluso+M%22">Macaluso M</searchLink>; Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham.<br /><searchLink fieldCode="AU" term="%22Mattingly+GW%22">Mattingly GW</searchLink>; Midwest Research Group-St Charles Psychiatric Associates, St Charles, Missouri.<br /><searchLink fieldCode="AU" term="%22Shelton+RC%22">Shelton RC</searchLink>; Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham School of Medicine, Huntsville Regional Medical Campus, Huntsville.<br /><searchLink fieldCode="AU" term="%22Zajecka+JM%22">Zajecka JM</searchLink>; Department of Psychiatry, Rush University, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Fu+DJ%22">Fu DJ</searchLink>; Department of Neuroscience, Johnson & Johnson, Titusville, New Jersey.
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        Value: 10.1001/jamapsychiatry.2025.1317
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              Text: 2025 Sep 01
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