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Failed cellular surveillance enables pathogenic matrix deposition in a COL2A1-related osteoarthritis.

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Title: Failed cellular surveillance enables pathogenic matrix deposition in a COL2A1-related osteoarthritis.
Authors: Yammine KM; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States., Mirda Abularach S; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States., Xiong M; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States., Kim SY; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States., Bikovtseva AA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States., Butty VL; BioMicro Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States., Schiavoni RP; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States., Bateman JF; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia., Lamandé SR; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Murdoch Children's Research Institute, Parkville, Victoria, Australia., Shoulders MD; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States. Electronic address: mshoulde@mit.edu.
Source: The Journal of biological chemistry [J Biol Chem] 2025 Aug; Vol. 301 (8), pp. 110436. Date of Electronic Publication: 2025 Jun 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Failed cellular surveillance enables pathogenic matrix deposition in a COL2A1-related osteoarthritis.
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  Data: <searchLink fieldCode="AU" term="%22Yammine+KM%22">Yammine KM</searchLink>; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Mirda+Abularach+S%22">Mirda Abularach S</searchLink>; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Xiong+M%22">Xiong M</searchLink>; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Kim+SY%22">Kim SY</searchLink>; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Bikovtseva+AA%22">Bikovtseva AA</searchLink>; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Butty+VL%22">Butty VL</searchLink>; BioMicro Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Schiavoni+RP%22">Schiavoni RP</searchLink>; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Bateman+JF%22">Bateman JF</searchLink>; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Lamandé+SR%22">Lamandé SR</searchLink>; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Murdoch Children's Research Institute, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Shoulders+MD%22">Shoulders MD</searchLink>; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States. Electronic address: mshoulde@mit.edu.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2025 Aug; Vol. 301 (8), pp. 110436. <i>Date of Electronic Publication: </i>2025 Jun 30.
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  Data: Journal Article; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985121R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1083-351X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219258%22">00219258 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jbc.2025.110436
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        Text: English
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              Text: 2025 Aug
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