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Effect of targeting normoxemia on supplemental oxygen-free days for adults with acute thermal burns: A stepped wedge cluster randomized clinical trial.

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Title: Effect of targeting normoxemia on supplemental oxygen-free days for adults with acute thermal burns: A stepped wedge cluster randomized clinical trial.
Authors: Douin DJ; From the Department of Anesthesiology (D.J.D.), University of Colorado School of Medicine, Aurora, Colorado; Department of Biostatistics (J.D.R.), University of Michigan School of Public Health, Ann Arbor, Michigan; Department of Biostatistics and Informatics (M.X., C.L.J., L.E.B.), Colorado School of Public Health; Department of Emergency Medicine (E.L.A., J.C., A.S., V.S.B., A.A.G.), University of Colorado School of Medicine, Aurora, Colorado; Department of Biomedical Informatics (A.C.C.), Vanderbilt University Medical Center, Nashville, Tennessee; Department of Biostatistics and Informatics (J.L.W.), Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado; Department of Surgery (R.T.B.), Vanderbilt University Medical Center, Nashville, Tennessee; US Army Burn Center, US Army Institute of Surgical Research (G.W.B.), Houston, Texas; Department of Medicine (G.W.B.), Meadville Medical Center, Meadville; Department of Surgery (A.C.C., J.Z.), University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Department of Surgery (E.L.D., J.C.S.), University of Cincinnati, Cincinnati, Ohio; Department of Surgery (J.H., J.O.J.), University of Alabama at Birmingham, Birmingham, Alabama; Vanderbilt Institute for Clinical & Translational Research (W.H.S.), Vanderbilt University Medical Center, Nashville, Tennessee; Department of Surgery (A.J.W.), University of Colorado School of Medicine, Aurora, Colorado; US Army Institute of Surgical Research (S.G.S.), Department of Emergency Medicine (S.G.S.), Brooke Army Medical Center, Joint Base San Antonio-Fort Sam Houston, San Antonio, Texas; Center for COMBAT Research (V.S.B.), University of Colorado School of Medicine, Aurora, Colorado; US Army Burn Center (L.C.), US Army Institute of Surgical Research, Fort Sam Houston, Texas., Rice JD, Xiao M, Jackson CL, Anderson EL, Cheng AC, Cwik J, Beaty LE, Wild JL, Beyene RT, Britton GW, Corcos AC, Dale EL, Hwang J, Jansen JO, Self WH, Slater JC, Steinwand A, Wiktor AJ, Ziembicki J, Schauer SG, Bebarta VS, Cancio L, Ginde AA
Corporate Authors: Strategy to Avoid Excessive Oxygen (SAVE-O2) Investigators
Source: The journal of trauma and acute care surgery [J Trauma Acute Care Surg] 2025 Oct 01; Vol. 99 (4), pp. 619-627. Date of Electronic Publication: 2025 Jul 03.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 101570622 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-0763 (Electronic) Linking ISSN: 21630755 NLM ISO Abbreviation: J Trauma Acute Care Surg Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of targeting normoxemia on supplemental oxygen-free days for adults with acute thermal burns: A stepped wedge cluster randomized clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Douin+DJ%22">Douin DJ</searchLink>; From the Department of Anesthesiology (D.J.D.), University of Colorado School of Medicine, Aurora, Colorado; Department of Biostatistics (J.D.R.), University of Michigan School of Public Health, Ann Arbor, Michigan; Department of Biostatistics and Informatics (M.X., C.L.J., L.E.B.), Colorado School of Public Health; Department of Emergency Medicine (E.L.A., J.C., A.S., V.S.B., A.A.G.), University of Colorado School of Medicine, Aurora, Colorado; Department of Biomedical Informatics (A.C.C.), Vanderbilt University Medical Center, Nashville, Tennessee; Department of Biostatistics and Informatics (J.L.W.), Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado; Department of Surgery (R.T.B.), Vanderbilt University Medical Center, Nashville, Tennessee; US Army Burn Center, US Army Institute of Surgical Research (G.W.B.), Houston, Texas; Department of Medicine (G.W.B.), Meadville Medical Center, Meadville; Department of Surgery (A.C.C., J.Z.), University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Department of Surgery (E.L.D., J.C.S.), University of Cincinnati, Cincinnati, Ohio; Department of Surgery (J.H., J.O.J.), University of Alabama at Birmingham, Birmingham, Alabama; Vanderbilt Institute for Clinical & Translational Research (W.H.S.), Vanderbilt University Medical Center, Nashville, Tennessee; Department of Surgery (A.J.W.), University of Colorado School of Medicine, Aurora, Colorado; US Army Institute of Surgical Research (S.G.S.), Department of Emergency Medicine (S.G.S.), Brooke Army Medical Center, Joint Base San Antonio-Fort Sam Houston, San Antonio, Texas; Center for COMBAT Research (V.S.B.), University of Colorado School of Medicine, Aurora, Colorado; US Army Burn Center (L.C.), US Army Institute of Surgical Research, Fort Sam Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Rice+JD%22">Rice JD</searchLink><br /><searchLink fieldCode="AU" term="%22Xiao+M%22">Xiao M</searchLink><br /><searchLink fieldCode="AU" term="%22Jackson+CL%22">Jackson CL</searchLink><br /><searchLink fieldCode="AU" term="%22Anderson+EL%22">Anderson EL</searchLink><br /><searchLink fieldCode="AU" term="%22Cheng+AC%22">Cheng AC</searchLink><br /><searchLink fieldCode="AU" term="%22Cwik+J%22">Cwik J</searchLink><br /><searchLink fieldCode="AU" term="%22Beaty+LE%22">Beaty LE</searchLink><br /><searchLink fieldCode="AU" term="%22Wild+JL%22">Wild JL</searchLink><br /><searchLink fieldCode="AU" term="%22Beyene+RT%22">Beyene RT</searchLink><br /><searchLink fieldCode="AU" term="%22Britton+GW%22">Britton GW</searchLink><br /><searchLink fieldCode="AU" term="%22Corcos+AC%22">Corcos AC</searchLink><br /><searchLink fieldCode="AU" term="%22Dale+EL%22">Dale EL</searchLink><br /><searchLink fieldCode="AU" term="%22Hwang+J%22">Hwang J</searchLink><br /><searchLink fieldCode="AU" term="%22Jansen+JO%22">Jansen JO</searchLink><br /><searchLink fieldCode="AU" term="%22Self+WH%22">Self WH</searchLink><br /><searchLink fieldCode="AU" term="%22Slater+JC%22">Slater JC</searchLink><br /><searchLink fieldCode="AU" term="%22Steinwand+A%22">Steinwand A</searchLink><br /><searchLink fieldCode="AU" term="%22Wiktor+AJ%22">Wiktor AJ</searchLink><br /><searchLink fieldCode="AU" term="%22Ziembicki+J%22">Ziembicki J</searchLink><br /><searchLink fieldCode="AU" term="%22Schauer+SG%22">Schauer SG</searchLink><br /><searchLink fieldCode="AU" term="%22Bebarta+VS%22">Bebarta VS</searchLink><br /><searchLink fieldCode="AU" term="%22Cancio+L%22">Cancio L</searchLink><br /><searchLink fieldCode="AU" term="%22Ginde+AA%22">Ginde AA</searchLink>
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  Data: <searchLink fieldCode="CA" term="%22Strategy+to+Avoid+Excessive+Oxygen+%28SAVE-O2%29+Investigators%22">Strategy to Avoid Excessive Oxygen (SAVE-O2) Investigators</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101570622%22">The journal of trauma and acute care surgery</searchLink> [J Trauma Acute Care Surg] 2025 Oct 01; Vol. 99 (4), pp. 619-627. <i>Date of Electronic Publication: </i>2025 Jul 03.
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  Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott%2C+Williams+%26+Wilkins%22">Lippincott, Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101570622 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2163-0763 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221630755%22">21630755 </searchLink><i>NLM ISO Abbreviation: </i>J Trauma Acute Care Surg <i>Subsets: </i>MEDLINE
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