Polystyrene Nanoplastics Exacerbate HFD-induced MASLD by Reducing Cathepsin Activity and Triggering Large Vacuole Formation via Impaired Lysosomal Acidification.
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| Title: | Polystyrene Nanoplastics Exacerbate HFD-induced MASLD by Reducing Cathepsin Activity and Triggering Large Vacuole Formation via Impaired Lysosomal Acidification. |
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| Authors: | Ahn J; Center for Gene and Cell Therapy, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea., Ryu K; Center for Gene and Cell Therapy, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea., Kim H; Korea Bioinformation Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea., Seo HW; Infectious Diseases Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea., Jang M; Center for Gene and Cell Therapy, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea., Kim SH; Center for Gene and Cell Therapy, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea., Park Y; Center for Gene and Cell Therapy, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.; Advanced Bioconvergence Department, Korea University of Science and Technology (UST), Daejeon 34141, Republic of Korea., Son MJ; Center for Gene and Cell Therapy, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.; Advanced Bioconvergence Department, Korea University of Science and Technology (UST), Daejeon 34141, Republic of Korea., Lee HJ; Center for Gene and Cell Therapy, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea., Kwon OS; Center for Gene and Cell Therapy, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.; Advanced Bioconvergence Department, Korea University of Science and Technology (UST), Daejeon 34141, Republic of Korea., Chung KS; Center for Gene and Cell Therapy, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.; Advanced Bioconvergence Department, Korea University of Science and Technology (UST), Daejeon 34141, Republic of Korea.; Biomedical Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea. |
| Source: | International journal of biological sciences [Int J Biol Sci] 2025 Jun 09; Vol. 21 (9), pp. 3867-3885. Date of Electronic Publication: 2025 Jun 09 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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