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Dihydrotanshinone I inhibits ovarian tumor growth by suppressing ITGB1/FAK-mediated extracellular matrix signaling.

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Title: Dihydrotanshinone I inhibits ovarian tumor growth by suppressing ITGB1/FAK-mediated extracellular matrix signaling.
Authors: Han B; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China., Sun C; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China., Yang R; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China., Li X; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China., Kang J; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China., Cai J; National Key Laboratory of Chinese Medicine Modernization, Pharmacology & Toxicology Department of Academy, Tasly Pharmaceuticals Co., Ltd., Tianjin 300410, China., Zhou S; National Key Laboratory of Chinese Medicine Modernization, Pharmacology & Toxicology Department of Academy, Tasly Pharmaceuticals Co., Ltd., Tianjin 300410, China., Wang G; National Key Laboratory of Chinese Medicine Modernization, Pharmacology & Toxicology Department of Academy, Tasly Pharmaceuticals Co., Ltd., Tianjin 300410, China., Wang J; National Key Laboratory of Chinese Medicine Modernization, Pharmacology & Toxicology Department of Academy, Tasly Pharmaceuticals Co., Ltd., Tianjin 300410, China., Zhang J; Oncology Department, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, Wenzhou, 325000, China., Sun Y; Oncology Department, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, Wenzhou, 325000, China., Kai G; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China. Electronic address: kaiguoyin@163.com.
Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Sep; Vol. 145, pp. 157023. Date of Electronic Publication: 2025 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Dihydrotanshinone I inhibits ovarian tumor growth by suppressing ITGB1/FAK-mediated extracellular matrix signaling.
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  Data: <searchLink fieldCode="AU" term="%22Han+B%22">Han B</searchLink>; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China.<br /><searchLink fieldCode="AU" term="%22Sun+C%22">Sun C</searchLink>; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China.<br /><searchLink fieldCode="AU" term="%22Yang+R%22">Yang R</searchLink>; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China.<br /><searchLink fieldCode="AU" term="%22Kang+J%22">Kang J</searchLink>; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China.<br /><searchLink fieldCode="AU" term="%22Cai+J%22">Cai J</searchLink>; National Key Laboratory of Chinese Medicine Modernization, Pharmacology & Toxicology Department of Academy, Tasly Pharmaceuticals Co., Ltd., Tianjin 300410, China.<br /><searchLink fieldCode="AU" term="%22Zhou+S%22">Zhou S</searchLink>; National Key Laboratory of Chinese Medicine Modernization, Pharmacology & Toxicology Department of Academy, Tasly Pharmaceuticals Co., Ltd., Tianjin 300410, China.<br /><searchLink fieldCode="AU" term="%22Wang+G%22">Wang G</searchLink>; National Key Laboratory of Chinese Medicine Modernization, Pharmacology & Toxicology Department of Academy, Tasly Pharmaceuticals Co., Ltd., Tianjin 300410, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; National Key Laboratory of Chinese Medicine Modernization, Pharmacology & Toxicology Department of Academy, Tasly Pharmaceuticals Co., Ltd., Tianjin 300410, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Oncology Department, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, Wenzhou, 325000, China.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Oncology Department, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, Wenzhou, 325000, China.<br /><searchLink fieldCode="AU" term="%22Kai+G%22">Kai G</searchLink>; Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation, Institute of Chinese Medicine Resource Innovation and Quality Evaluation, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China. Electronic address: kaiguoyin@163.com.
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  Data: <searchLink fieldCode="JN" term="%229438794%22">Phytomedicine : international journal of phytotherapy and phytopharmacology</searchLink> [Phytomedicine] 2025 Sep; Vol. 145, pp. 157023. <i>Date of Electronic Publication: </i>2025 Jun 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Urban+%26+Fischer+Verlag%22">Urban & Fischer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9438794 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1618-095X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209447113%22">09447113 </searchLink><i>NLM ISO Abbreviation: </i>Phytomedicine <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.phymed.2025.157023
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      – Code: eng
        Text: English
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        StartPage: 157023
    Titles:
      – TitleFull: Dihydrotanshinone I inhibits ovarian tumor growth by suppressing ITGB1/FAK-mediated extracellular matrix signaling.
        Type: main
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          Name:
            NameFull: Han B
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          Dates:
            – D: 01
              M: 09
              Text: 2025 Sep
              Type: published
              Y: 2025
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              Value: 145
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            – TitleFull: Phytomedicine : international journal of phytotherapy and phytopharmacology
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