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A Phase-2B Double-Blind Randomized International Prospective Trial of Inebilizumab in NMDAR Encephalitis: The ExTINGUISH Trial.

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Title: A Phase-2B Double-Blind Randomized International Prospective Trial of Inebilizumab in NMDAR Encephalitis: The ExTINGUISH Trial.
Authors: Wong KH; Department of Neurology, University of Utah, Salt Lake City, UT.; Salt Lake City Veterans Affairs Health System Medical Center, Salt Lake City, UT., Day GS; Department of Neurology, Mayo Clinic in Florida, Jacksonville, FL., Torner JC; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA., Cudkowicz M; Department of Neurology, NeuroNEXT Clinical Coordinating Center, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Harvard Medical School, Boston, MA., Coffey CS; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA., Cho HJS; The National Institute of Neurological Disorders and Stroke (NINDS), of the National Institutes of Health, Bethesda, MD., Utz U; The National Institute of Neurological Disorders and Stroke (NINDS), of the National Institutes of Health, Bethesda, MD., Clifford DB; Department of Neurology, Washington University, St. Louis, MO., Katz E; Formerly with Viela Bio at Time of Contributions; Viela Bio Was Subsequently Acquired By Horizon and Later Amgen, Thousand Oaks, CA., Ratchford J; Formerly with Viela Bio at Time of Contributions; Viela Bio Was Subsequently Acquired By Horizon and Later Amgen, Thousand Oaks, CA., Flavin S; Amgen, Thousand Oaks, CA., Dialino-Felix A; Amgen, Thousand Oaks, CA., Dill LM; Amgen, Thousand Oaks, CA., Kamp C; Clinical Materials Services Unit (CMSU) in the Center for Human Experimental Therapeutics (CHET), University of Rochester, Rochester, NY., Klawiter EC; Department of Neurology, NeuroNEXT Clinical Coordinating Center, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Harvard Medical School, Boston, MA., Singleton JR; Department of Neurology, University of Utah, Salt Lake City, UT.; Salt Lake City Veterans Affairs Health System Medical Center, Salt Lake City, UT., Fedler J; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA., Klingner EA; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA., Ecklund D; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA., Klements D; Department of Neurology, NeuroNEXT Clinical Coordinating Center, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Harvard Medical School, Boston, MA., Costigan M; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA., Steinhart E; Department of Neurology, NeuroNEXT Clinical Coordinating Center, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Harvard Medical School, Boston, MA., Pearson B; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA., Desir C; Department of Neurology, NeuroNEXT Clinical Coordinating Center, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Harvard Medical School, Boston, MA., Dalmau JO; IDIBAPS-Hospital Clinic, University of Barcelona, Barcelona, Spain., Titulaer MJ; Department of Neurology, University Erasmus Medical Center, Rotterdam, the Netherlands., Clardy SL; Department of Neurology, University of Utah, Salt Lake City, UT.; Salt Lake City Veterans Affairs Health System Medical Center, Salt Lake City, UT.
Source: Neurology open access [Neurol Open Access] 2025 Jun; Vol. 1 (2). Date of Electronic Publication: 2025 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health Inc. on behalf of the American Academy of Neurology Country of Publication: United States NLM ID: 9919033199906676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2998-7601 (Electronic) Linking ISSN: 29987601 NLM ISO Abbreviation: Neurol Open Access Subsets: PubMed not MEDLINE
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  Data: A Phase-2B Double-Blind Randomized International Prospective Trial of Inebilizumab in NMDAR Encephalitis: The ExTINGUISH Trial.
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  Data: <searchLink fieldCode="AU" term="%22Wong+KH%22">Wong KH</searchLink>; Department of Neurology, University of Utah, Salt Lake City, UT.; Salt Lake City Veterans Affairs Health System Medical Center, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Day+GS%22">Day GS</searchLink>; Department of Neurology, Mayo Clinic in Florida, Jacksonville, FL.<br /><searchLink fieldCode="AU" term="%22Torner+JC%22">Torner JC</searchLink>; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA.<br /><searchLink fieldCode="AU" term="%22Cudkowicz+M%22">Cudkowicz M</searchLink>; Department of Neurology, NeuroNEXT Clinical Coordinating Center, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Coffey+CS%22">Coffey CS</searchLink>; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA.<br /><searchLink fieldCode="AU" term="%22Cho+HJS%22">Cho HJS</searchLink>; The National Institute of Neurological Disorders and Stroke (NINDS), of the National Institutes of Health, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Utz+U%22">Utz U</searchLink>; The National Institute of Neurological Disorders and Stroke (NINDS), of the National Institutes of Health, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Clifford+DB%22">Clifford DB</searchLink>; Department of Neurology, Washington University, St. Louis, MO.<br /><searchLink fieldCode="AU" term="%22Katz+E%22">Katz E</searchLink>; Formerly with Viela Bio at Time of Contributions; Viela Bio Was Subsequently Acquired By Horizon and Later Amgen, Thousand Oaks, CA.<br /><searchLink fieldCode="AU" term="%22Ratchford+J%22">Ratchford J</searchLink>; Formerly with Viela Bio at Time of Contributions; Viela Bio Was Subsequently Acquired By Horizon and Later Amgen, Thousand Oaks, CA.<br /><searchLink fieldCode="AU" term="%22Flavin+S%22">Flavin S</searchLink>; Amgen, Thousand Oaks, CA.<br /><searchLink fieldCode="AU" term="%22Dialino-Felix+A%22">Dialino-Felix A</searchLink>; Amgen, Thousand Oaks, CA.<br /><searchLink fieldCode="AU" term="%22Dill+LM%22">Dill LM</searchLink>; Amgen, Thousand Oaks, CA.<br /><searchLink fieldCode="AU" term="%22Kamp+C%22">Kamp C</searchLink>; Clinical Materials Services Unit (CMSU) in the Center for Human Experimental Therapeutics (CHET), University of Rochester, Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Klawiter+EC%22">Klawiter EC</searchLink>; Department of Neurology, NeuroNEXT Clinical Coordinating Center, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Singleton+JR%22">Singleton JR</searchLink>; Department of Neurology, University of Utah, Salt Lake City, UT.; Salt Lake City Veterans Affairs Health System Medical Center, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Fedler+J%22">Fedler J</searchLink>; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA.<br /><searchLink fieldCode="AU" term="%22Klingner+EA%22">Klingner EA</searchLink>; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA.<br /><searchLink fieldCode="AU" term="%22Ecklund+D%22">Ecklund D</searchLink>; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA.<br /><searchLink fieldCode="AU" term="%22Klements+D%22">Klements D</searchLink>; Department of Neurology, NeuroNEXT Clinical Coordinating Center, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Costigan+M%22">Costigan M</searchLink>; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA.<br /><searchLink fieldCode="AU" term="%22Steinhart+E%22">Steinhart E</searchLink>; Department of Neurology, NeuroNEXT Clinical Coordinating Center, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Pearson+B%22">Pearson B</searchLink>; NeuroNEXT Data Coordinating Center, Clinical Trials Statistical Data Management Center, Department of Biostatistics, University of Iowa, IA.<br /><searchLink fieldCode="AU" term="%22Desir+C%22">Desir C</searchLink>; Department of Neurology, NeuroNEXT Clinical Coordinating Center, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Dalmau+JO%22">Dalmau JO</searchLink>; IDIBAPS-Hospital Clinic, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Titulaer+MJ%22">Titulaer MJ</searchLink>; Department of Neurology, University Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Clardy+SL%22">Clardy SL</searchLink>; Department of Neurology, University of Utah, Salt Lake City, UT.; Salt Lake City Veterans Affairs Health System Medical Center, Salt Lake City, UT.
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  Data: <searchLink fieldCode="JN" term="%229919033199906676%22">Neurology open access</searchLink> [Neurol Open Access] 2025 Jun; Vol. 1 (2). <i>Date of Electronic Publication: </i>2025 Apr 23.
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