SARC028 Samples Reveal an Interplay between TGF-β, IFN Signaling, and Low HLA Class I Expression as Contributors to Ewing Sarcoma Checkpoint Blockade Resistance.
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| Title: | SARC028 Samples Reveal an Interplay between TGF-β, IFN Signaling, and Low HLA Class I Expression as Contributors to Ewing Sarcoma Checkpoint Blockade Resistance. |
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| Authors: | Daley JD; University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Mukherjee E; Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania., Ferraro D; Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania., Bhaskar S; Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania., Green A; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania., Meyer EM; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Tawbi H; UT MD Anderson Cancer Center, Houston, Texas., Burgess M; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Bruno TC; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Cillo AR; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.; Center for Systems Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania., Bailey KM; University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. |
| Source: | Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Sep 02; Vol. 31 (17), pp. 3805-3816. |
| Publication Type: | Journal Article; Clinical Trial, Phase II |
| Journal Info: | Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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