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A global genetic interaction map of a human cell reveals conserved principles of genetic networks.

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Title: A global genetic interaction map of a human cell reveals conserved principles of genetic networks.
Authors: Billmann M; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Institute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn; Bonn, Germany., Costanzo M; Donnelly Centre, University of Toronto; Toronto ON, Canada., Zhang X; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Hassan AZ; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Rahman M; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Brown KR; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Chan KS; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Tong AHY; Donnelly Centre, University of Toronto; Toronto ON, Canada., Pons C; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute for Science and Technology; Barcelona, Spain., Ward HN; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA., Ross C; Donnelly Centre, University of Toronto; Toronto ON, Canada., van Leeuwen J; Donnelly Centre, University of Toronto; Toronto ON, Canada., Aregger M; Donnelly Centre, University of Toronto; Toronto ON, Canada., Lawson KA; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Mair B; Donnelly Centre, University of Toronto; Toronto ON, Canada., Roth AF; Department of Pharmacology, Wayne State University School of Medicine; Detroit MI, USA., Sen NE; Department of Molecular and Cellular Biology, University of Geneva; Geneva, Switzerland., Forster D; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Tan G; Donnelly Centre, University of Toronto; Toronto ON, Canada., Mero P; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Masud SN; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Lee Y; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA., Aguilera-Uribe M; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Usaj M; Donnelly Centre, University of Toronto; Toronto ON, Canada., Almeida SMT; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Aulakh K; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Bhojoo U; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Birkadze S; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Budijono N; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Cai X; Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology; Wuhan, China., Caumanns JJ; Donnelly Centre, University of Toronto; Toronto ON, Canada., Chandrashekhar M; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Chang D; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Climie R; Donnelly Centre, University of Toronto; Toronto ON, Canada., Dasgupta K; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Drazic A; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biomedicine, University of Bergen; Bergen, Norway., Rojas Echenique JI; Donnelly Centre, University of Toronto; Toronto ON, Canada., Gacesa R; Donnelly Centre, University of Toronto; Toronto ON, Canada., Granda Farias A; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Habsid A; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Horecka I; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Kantautas K; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Ji F; Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology; Wuhan, China., Kim DK; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Surgery, McGill University. Cancer Research Program, Research Institute of McGill University Health Centre; Montreal QC, Canada., Lee SY; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Liang W; Donnelly Centre, University of Toronto; Toronto ON, Canada., Lim J; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Lin K; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA., Lu X; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Nami B; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Nixon A; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Mikolajewicz N; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Nedyalkova L; Donnelly Centre, University of Toronto; Toronto ON, Canada., Rohde T; Institute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn; Bonn, Germany., Sartori Rodrigues M; Donnelly Centre, University of Toronto; Toronto ON, Canada., Soste M; Donnelly Centre, University of Toronto; Toronto ON, Canada., Schultz E; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Wang W; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Seetharaman A; Donnelly Centre, University of Toronto; Toronto ON, Canada., Shuteriqi E; Donnelly Centre, University of Toronto; Toronto ON, Canada., Sizova O; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Thomson Taylor D; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Institute for Biomedical Engineering, University of Toronto; Toronto, ON, Canada., Tereshchenko M; Department of Biochemistry, University of Toronto; Toronto ON, Canada., Tieu D; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Turowec J; Donnelly Centre, University of Toronto; Toronto ON, Canada., Ubhi T; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biochemistry, University of Toronto; Toronto ON, Canada., Varland S; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biomedicine, University of Bergen; Bergen, Norway., Wang KE; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Wang ZY; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Wei J; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Xiao YX; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Brown GW; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biochemistry, University of Toronto; Toronto ON, Canada., Cravatt BF; Department of Chemistry, The Scripps Research Institute; La Jolla, CA, USA., Dixon SJ; Department of Biology, Stanford University; Stanford CA, USA., Wyatt HDM; Department of Biochemistry, University of Toronto; Toronto ON, Canada., Röst HL; Donnelly Centre, University of Toronto; Toronto ON, Canada., Roth FP; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Xia T; School of Software engineering, Huazhong University of Science and Technology; Wuhan, China., Bader GD; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Loewith R; Department of Molecular and Cellular Biology, University of Geneva; Geneva, Switzerland., Davis NG; Department of Pharmacology, Wayne State University School of Medicine; Detroit MI, USA., Andrews B; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Myers CL; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA., Moffat J; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.; Institute for Biomedical Engineering, University of Toronto; Toronto, ON, Canada., Boone C; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.; RIKEN Center for Sustainable Resource Science; Wako 351-0198, Saitama, Japan.; Canadian Institute for Advanced Research (CIFAR).
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 02. Date of Electronic Publication: 2025 Jul 02.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40631273
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
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  Data: A global genetic interaction map of a human cell reveals conserved principles of genetic networks.
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  Data: <searchLink fieldCode="AU" term="%22Billmann+M%22">Billmann M</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Institute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn; Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Costanzo+M%22">Costanzo M</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Hassan+AZ%22">Hassan AZ</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Rahman+M%22">Rahman M</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Brown+KR%22">Brown KR</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Chan+KS%22">Chan KS</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Tong+AHY%22">Tong AHY</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Pons+C%22">Pons C</searchLink>; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute for Science and Technology; Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Ward+HN%22">Ward HN</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Ross+C%22">Ross C</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22van+Leeuwen+J%22">van Leeuwen J</searchLink>; 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Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Tan+G%22">Tan G</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Mero+P%22">Mero P</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Masud+SN%22">Masud SN</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Lee+Y%22">Lee Y</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Aguilera-Uribe+M%22">Aguilera-Uribe M</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Usaj+M%22">Usaj M</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Almeida+SMT%22">Almeida SMT</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Aulakh+K%22">Aulakh K</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Bhojoo+U%22">Bhojoo U</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Birkadze+S%22">Birkadze S</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Budijono+N%22">Budijono N</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Cai+X%22">Cai X</searchLink>; Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology; Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Caumanns+JJ%22">Caumanns JJ</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Chandrashekhar+M%22">Chandrashekhar M</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Chang+D%22">Chang D</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Climie+R%22">Climie R</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Dasgupta+K%22">Dasgupta K</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Drazic+A%22">Drazic A</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biomedicine, University of Bergen; Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Rojas+Echenique+JI%22">Rojas Echenique JI</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Gacesa+R%22">Gacesa R</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Granda+Farias+A%22">Granda Farias A</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Habsid+A%22">Habsid A</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Horecka+I%22">Horecka I</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Kantautas+K%22">Kantautas K</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Ji+F%22">Ji F</searchLink>; Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology; Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Kim+DK%22">Kim DK</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Surgery, McGill University. 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Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Nami+B%22">Nami B</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Nixon+A%22">Nixon A</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Mikolajewicz+N%22">Mikolajewicz N</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Nedyalkova+L%22">Nedyalkova L</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Rohde+T%22">Rohde T</searchLink>; Institute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn; Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Sartori+Rodrigues+M%22">Sartori Rodrigues M</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Soste+M%22">Soste M</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Schultz+E%22">Schultz E</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Seetharaman+A%22">Seetharaman A</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Shuteriqi+E%22">Shuteriqi E</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Sizova+O%22">Sizova O</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Thomson+Taylor+D%22">Thomson Taylor D</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Institute for Biomedical Engineering, University of Toronto; Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Tereshchenko+M%22">Tereshchenko M</searchLink>; Department of Biochemistry, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Tieu+D%22">Tieu D</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Turowec+J%22">Turowec J</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Ubhi+T%22">Ubhi T</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biochemistry, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Varland+S%22">Varland S</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biomedicine, University of Bergen; Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Wang+KE%22">Wang KE</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+ZY%22">Wang ZY</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Wei+J%22">Wei J</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Xiao+YX%22">Xiao YX</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Brown+GW%22">Brown GW</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biochemistry, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Cravatt+BF%22">Cravatt BF</searchLink>; Department of Chemistry, The Scripps Research Institute; La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Dixon+SJ%22">Dixon SJ</searchLink>; Department of Biology, Stanford University; Stanford CA, USA.<br /><searchLink fieldCode="AU" term="%22Wyatt+HDM%22">Wyatt HDM</searchLink>; Department of Biochemistry, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Röst+HL%22">Röst HL</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Roth+FP%22">Roth FP</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Xia+T%22">Xia T</searchLink>; School of Software engineering, Huazhong University of Science and Technology; Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Bader+GD%22">Bader GD</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Loewith+R%22">Loewith R</searchLink>; Department of Molecular and Cellular Biology, University of Geneva; Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Davis+NG%22">Davis NG</searchLink>; Department of Pharmacology, Wayne State University School of Medicine; Detroit MI, USA.<br /><searchLink fieldCode="AU" term="%22Andrews+B%22">Andrews B</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.<br /><searchLink fieldCode="AU" term="%22Myers+CL%22">Myers CL</searchLink>; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Moffat+J%22">Moffat J</searchLink>; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.; Institute for Biomedical Engineering, University of Toronto; Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Boone+C%22">Boone C</searchLink>; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.; RIKEN Center for Sustainable Resource Science; Wako 351-0198, Saitama, Japan.; Canadian Institute for Advanced Research (CIFAR).
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        Value: 10.1101/2025.06.30.662193
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        Text: English
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      – TitleFull: A global genetic interaction map of a human cell reveals conserved principles of genetic networks.
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
          Name:
            NameFull: Cravatt BF
      – PersonEntity:
          Name:
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      – PersonEntity:
          Name:
            NameFull: Wyatt HDM
      – PersonEntity:
          Name:
            NameFull: Röst HL
      – PersonEntity:
          Name:
            NameFull: Roth FP
      – PersonEntity:
          Name:
            NameFull: Xia T
      – PersonEntity:
          Name:
            NameFull: Bader GD
      – PersonEntity:
          Name:
            NameFull: Loewith R
      – PersonEntity:
          Name:
            NameFull: Davis NG
      – PersonEntity:
          Name:
            NameFull: Andrews B
      – PersonEntity:
          Name:
            NameFull: Myers CL
      – PersonEntity:
          Name:
            NameFull: Moffat J
      – PersonEntity:
          Name:
            NameFull: Boone C
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 02
              M: 07
              Text: 2025 Jul 02
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
          Titles:
            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
ResultId 1