A global genetic interaction map of a human cell reveals conserved principles of genetic networks.
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| Title: | A global genetic interaction map of a human cell reveals conserved principles of genetic networks. |
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| Authors: | Billmann M; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Institute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn; Bonn, Germany., Costanzo M; Donnelly Centre, University of Toronto; Toronto ON, Canada., Zhang X; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Hassan AZ; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Rahman M; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Brown KR; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Chan KS; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Tong AHY; Donnelly Centre, University of Toronto; Toronto ON, Canada., Pons C; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute for Science and Technology; Barcelona, Spain., Ward HN; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA., Ross C; Donnelly Centre, University of Toronto; Toronto ON, Canada., van Leeuwen J; Donnelly Centre, University of Toronto; Toronto ON, Canada., Aregger M; Donnelly Centre, University of Toronto; Toronto ON, Canada., Lawson KA; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Mair B; Donnelly Centre, University of Toronto; Toronto ON, Canada., Roth AF; Department of Pharmacology, Wayne State University School of Medicine; Detroit MI, USA., Sen NE; Department of Molecular and Cellular Biology, University of Geneva; Geneva, Switzerland., Forster D; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Tan G; Donnelly Centre, University of Toronto; Toronto ON, Canada., Mero P; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Masud SN; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Lee Y; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA., Aguilera-Uribe M; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Usaj M; Donnelly Centre, University of Toronto; Toronto ON, Canada., Almeida SMT; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Aulakh K; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Bhojoo U; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Birkadze S; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Budijono N; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Cai X; Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology; Wuhan, China., Caumanns JJ; Donnelly Centre, University of Toronto; Toronto ON, Canada., Chandrashekhar M; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Chang D; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Climie R; Donnelly Centre, University of Toronto; Toronto ON, Canada., Dasgupta K; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Drazic A; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biomedicine, University of Bergen; Bergen, Norway., Rojas Echenique JI; Donnelly Centre, University of Toronto; Toronto ON, Canada., Gacesa R; Donnelly Centre, University of Toronto; Toronto ON, Canada., Granda Farias A; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Habsid A; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Horecka I; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Kantautas K; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Ji F; Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology; Wuhan, China., Kim DK; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Surgery, McGill University. Cancer Research Program, Research Institute of McGill University Health Centre; Montreal QC, Canada., Lee SY; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Liang W; Donnelly Centre, University of Toronto; Toronto ON, Canada., Lim J; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Lin K; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA., Lu X; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Nami B; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Nixon A; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Mikolajewicz N; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Nedyalkova L; Donnelly Centre, University of Toronto; Toronto ON, Canada., Rohde T; Institute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn; Bonn, Germany., Sartori Rodrigues M; Donnelly Centre, University of Toronto; Toronto ON, Canada., Soste M; Donnelly Centre, University of Toronto; Toronto ON, Canada., Schultz E; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Wang W; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA., Seetharaman A; Donnelly Centre, University of Toronto; Toronto ON, Canada., Shuteriqi E; Donnelly Centre, University of Toronto; Toronto ON, Canada., Sizova O; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada., Thomson Taylor D; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Institute for Biomedical Engineering, University of Toronto; Toronto, ON, Canada., Tereshchenko M; Department of Biochemistry, University of Toronto; Toronto ON, Canada., Tieu D; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Turowec J; Donnelly Centre, University of Toronto; Toronto ON, Canada., Ubhi T; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biochemistry, University of Toronto; Toronto ON, Canada., Varland S; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biomedicine, University of Bergen; Bergen, Norway., Wang KE; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Wang ZY; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Wei J; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Xiao YX; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Brown GW; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Biochemistry, University of Toronto; Toronto ON, Canada., Cravatt BF; Department of Chemistry, The Scripps Research Institute; La Jolla, CA, USA., Dixon SJ; Department of Biology, Stanford University; Stanford CA, USA., Wyatt HDM; Department of Biochemistry, University of Toronto; Toronto ON, Canada., Röst HL; Donnelly Centre, University of Toronto; Toronto ON, Canada., Roth FP; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Xia T; School of Software engineering, Huazhong University of Science and Technology; Wuhan, China., Bader GD; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Loewith R; Department of Molecular and Cellular Biology, University of Geneva; Geneva, Switzerland., Davis NG; Department of Pharmacology, Wayne State University School of Medicine; Detroit MI, USA., Andrews B; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada., Myers CL; Department of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, MN, USA., Moffat J; Program in Genetics and Genome Biology, The Hospital for Sick Children; Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.; Institute for Biomedical Engineering, University of Toronto; Toronto, ON, Canada., Boone C; Donnelly Centre, University of Toronto; Toronto ON, Canada.; Department of Molecular Genetics, University of Toronto; Toronto ON, Canada.; RIKEN Center for Sustainable Resource Science; Wako 351-0198, Saitama, Japan.; Canadian Institute for Advanced Research (CIFAR). |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 02. Date of Electronic Publication: 2025 Jul 02. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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