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Clinical endpoints in pragmatic heart failure trials: From data collection to clinical endpoint classification.

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Title: Clinical endpoints in pragmatic heart failure trials: From data collection to clinical endpoint classification.
Authors: Kittipibul V; Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA., Van Spall HGC; Population Health Research Institute, Hamilton, Ontario, Canada.; Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada., Jones WS; Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA., Fudim M; Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA., Mentz RJ; Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA., Anstrom K; Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Pitt B; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Desvigne-Nickens P; Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA., Fleg JL; Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA., Hage C; Department of Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden., James S; Uppsala Clinical Research Center and Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden., Held C; Uppsala Clinical Research Center and Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden., Lund L; Department of Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden., DeVore A; Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Source: ESC heart failure [ESC Heart Fail] 2025 Oct; Vol. 12 (5), pp. 3250-3263. Date of Electronic Publication: 2025 Jul 09.
Publication Type: Journal Article; Review
Journal Info: Publisher: John Wiley & Sons Ltd on behalf of the European Society of Cardiology Country of Publication: England NLM ID: 101669191 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2055-5822 (Electronic) Linking ISSN: 20555822 NLM ISO Abbreviation: ESC Heart Fail Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kittipibul+V%22">Kittipibul V</searchLink>; Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Van+Spall+HGC%22">Van Spall HGC</searchLink>; Population Health Research Institute, Hamilton, Ontario, Canada.; Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Jones+WS%22">Jones WS</searchLink>; Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Fudim+M%22">Fudim M</searchLink>; Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Mentz+RJ%22">Mentz RJ</searchLink>; Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Anstrom+K%22">Anstrom K</searchLink>; Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Pitt+B%22">Pitt B</searchLink>; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Desvigne-Nickens+P%22">Desvigne-Nickens P</searchLink>; Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Fleg+JL%22">Fleg JL</searchLink>; Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Hage+C%22">Hage C</searchLink>; Department of Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22James+S%22">James S</searchLink>; Uppsala Clinical Research Center and Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Held+C%22">Held C</searchLink>; Uppsala Clinical Research Center and Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Lund+L%22">Lund L</searchLink>; Department of Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22DeVore+A%22">DeVore A</searchLink>; Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons+Ltd+on+behalf+of+the+European+Society+of+Cardiology%22">John Wiley & Sons Ltd on behalf of the European Society of Cardiology </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101669191 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2055-5822 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220555822%22">20555822 </searchLink><i>NLM ISO Abbreviation: </i>ESC Heart Fail <i>Subsets: </i>MEDLINE
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              Text: 2025 Oct
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