Phenome-wide association study identifies multiple traits associated with a polygenic risk score for colorectal cancer.

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Title: Phenome-wide association study identifies multiple traits associated with a polygenic risk score for colorectal cancer.
Authors: Rosenthal EA; Department of Medicine, Division of Medical Genetics, University of Washington Medical Center, Seattle, WA, USA. erosen@uw.edu., Wei WQ; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Luo Y; Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Namjou-Khales B; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Schaid DJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Esplin ED; Labcorp Genetics, San Francisco, CA, USA., Lape M; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Kottyan L; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Pacheco JA; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Weng C; Department of Biomedical Informatics, Columbia, New York, NY, USA., Gordon AS; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Kullo IJ; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Crosslin DR; Division of Biomedical Informatics and Genomics, School of Medicine, Tulane, New Orleans, LA, USA., Grady WM; Translational Sciences and Therapeutics Division and Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Division of Gastroenterology, University of Washington School of Medicine, Seattle, WA, USA., Hsu L; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, USA., Peters U; Division of Gastroenterology, University of Washington School of Medicine, Seattle, WA, USA.; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Jarvik GP; Department of Medicine, Division of Medical Genetics, University of Washington Medical Center, Seattle, WA, USA.; Department of Genome Sciences, University of Washington Medical Center, Seattle, WA, USA.
Source: Human genomics [Hum Genomics] 2025 Jul 09; Vol. 19 (1), pp. 77. Date of Electronic Publication: 2025 Jul 09.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101202210 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-7364 (Electronic) Linking ISSN: 14739542 NLM ISO Abbreviation: Hum Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phenome-wide association study identifies multiple traits associated with a polygenic risk score for colorectal cancer.
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  Data: <searchLink fieldCode="AU" term="%22Rosenthal+EA%22">Rosenthal EA</searchLink>; Department of Medicine, Division of Medical Genetics, University of Washington Medical Center, Seattle, WA, USA. erosen@uw.edu.<br /><searchLink fieldCode="AU" term="%22Wei+WQ%22">Wei WQ</searchLink>; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Luo+Y%22">Luo Y</searchLink>; Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Namjou-Khales+B%22">Namjou-Khales B</searchLink>; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Schaid+DJ%22">Schaid DJ</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Esplin+ED%22">Esplin ED</searchLink>; Labcorp Genetics, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lape+M%22">Lape M</searchLink>; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Kottyan+L%22">Kottyan L</searchLink>; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Pacheco+JA%22">Pacheco JA</searchLink>; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Weng+C%22">Weng C</searchLink>; Department of Biomedical Informatics, Columbia, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+AS%22">Gordon AS</searchLink>; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Kullo+IJ%22">Kullo IJ</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Crosslin+DR%22">Crosslin DR</searchLink>; Division of Biomedical Informatics and Genomics, School of Medicine, Tulane, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Grady+WM%22">Grady WM</searchLink>; Translational Sciences and Therapeutics Division and Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Division of Gastroenterology, University of Washington School of Medicine, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Hsu+L%22">Hsu L</searchLink>; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, USA.<br /><searchLink fieldCode="AU" term="%22Peters+U%22">Peters U</searchLink>; Division of Gastroenterology, University of Washington School of Medicine, Seattle, WA, USA.; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Jarvik+GP%22">Jarvik GP</searchLink>; Department of Medicine, Division of Medical Genetics, University of Washington Medical Center, Seattle, WA, USA.; Department of Genome Sciences, University of Washington Medical Center, Seattle, WA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101202210%22">Human genomics</searchLink> [Hum Genomics] 2025 Jul 09; Vol. 19 (1), pp. 77. <i>Date of Electronic Publication: </i>2025 Jul 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101202210 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-7364 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214739542%22">14739542 </searchLink><i>NLM ISO Abbreviation: </i>Hum Genomics <i>Subsets: </i>MEDLINE
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