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CAR19-T/NK cell and circular aptamer-drug conjugate (ApDC) combination treatment increases immunotherapy efficacy.

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Title: CAR19-T/NK cell and circular aptamer-drug conjugate (ApDC) combination treatment increases immunotherapy efficacy.
Authors: Kong LQ; College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian, China.; Department of Pediatric Surgery, Jining No.1 People's Hospital, Shandong, China.; Department of Pediatric Urological Surgery, Fujian Children's Hospital, Fujian, China., Chen SY; Department of Pediatric Urological Surgery, Fujian Children's Hospital, Fujian, China., Cui X; Department of Pediatric Urological Surgery, Fujian Children's Hospital, Fujian, China., Hu YH; Quanzhou Women's and Children's Hospital, Quanzhou, China., Wang L; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhu JY; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Guan LX; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Wang BK; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Yang LT; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Chen KM; College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian, China. chenkaiming0001@126.com.; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. chenkaiming0001@126.com., Zhou CM; College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian, China. jnyyxewk@126.com.; Department of Pediatric Urological Surgery, Fujian Children's Hospital, Fujian, China. jnyyxewk@126.com.
Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2025 Nov; Vol. 480 (11), pp. 5779-5791. Date of Electronic Publication: 2025 Jul 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CAR19-T/NK cell and circular aptamer-drug conjugate (ApDC) combination treatment increases immunotherapy efficacy.
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  Data: <searchLink fieldCode="AU" term="%22Kong+LQ%22">Kong LQ</searchLink>; College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian, China.; Department of Pediatric Surgery, Jining No.1 People's Hospital, Shandong, China.; Department of Pediatric Urological Surgery, Fujian Children's Hospital, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Chen+SY%22">Chen SY</searchLink>; Department of Pediatric Urological Surgery, Fujian Children's Hospital, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Cui+X%22">Cui X</searchLink>; Department of Pediatric Urological Surgery, Fujian Children's Hospital, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Hu+YH%22">Hu YH</searchLink>; Quanzhou Women's and Children's Hospital, Quanzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhu+JY%22">Zhu JY</searchLink>; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Guan+LX%22">Guan LX</searchLink>; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wang+BK%22">Wang BK</searchLink>; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+LT%22">Yang LT</searchLink>; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+KM%22">Chen KM</searchLink>; College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian, China. chenkaiming0001@126.com.; Key Laboratory of Pediatric Hematology and Oncology, Ministry of Health and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. chenkaiming0001@126.com.<br /><searchLink fieldCode="AU" term="%22Zhou+CM%22">Zhou CM</searchLink>; College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian, China. jnyyxewk@126.com.; Department of Pediatric Urological Surgery, Fujian Children's Hospital, Fujian, China. jnyyxewk@126.com.
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  Data: <searchLink fieldCode="JN" term="%220364456%22">Molecular and cellular biochemistry</searchLink> [Mol Cell Biochem] 2025 Nov; Vol. 480 (11), pp. 5779-5791. <i>Date of Electronic Publication: </i>2025 Jul 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>0364456 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-4919 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203008177%22">03008177 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cell Biochem <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1007/s11010-025-05347-3
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      – Code: eng
        Text: English
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      – TitleFull: CAR19-T/NK cell and circular aptamer-drug conjugate (ApDC) combination treatment increases immunotherapy efficacy.
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            – D: 01
              M: 11
              Text: 2025 Nov
              Type: published
              Y: 2025
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              Value: 1573-4919
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              Value: 480
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            – TitleFull: Molecular and cellular biochemistry
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