Targeting complement C3/C3aR pathway restores rejuvenation factor PF4 and mitigates neurocognitive impairments in age-related perioperative neurocognitive disorders.
Saved in:
| Title: | Targeting complement C3/C3aR pathway restores rejuvenation factor PF4 and mitigates neurocognitive impairments in age-related perioperative neurocognitive disorders. |
|---|---|
| Authors: | Wang JL; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Ye CH; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Teng ZF; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Zhou K; Department of Urology, Fujian Medical University Union hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Pan LL; Fujian Institute of Hematology, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China.; Fujian Provincial Key Laboratory on Hematology, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China.; Department of Hematology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Ouyan MD; Department of Emergency Surgery, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Zheng Z; Department of Oral Surgery, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Lu M; Department of Oral Surgery, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Li SL; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Zhang J; Center for Advanced Vision Science, University of Virginia, Charlottesville, VA, USA.; Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA., Zheng PC; Fujian Center for Safety Evaluation of New Drug, Fujian Medical University, Fuzhou, Fujian, China.; Fujian Key Laboratory of Natural Medicine Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, China., Zhang J; Center for Advanced Vision Science, University of Virginia, Charlottesville, VA, USA.; Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA., Zhang H; Fujian Key Laboratory of Natural Medicine Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, China., Lin MH; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Zhang LC; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Huang SS; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Ren XN; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Zheng N; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Wei WL; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China., Zhao Z; Center for Cellular Regulation and Molecular Pharmaceutics, School of Life and Health Sciences, Hubei University of Technology, Wuhan, 430068, China. zhaozhenhuan@hbut.edu.cn., Wang SB; Center for Advanced Vision Science, University of Virginia, Charlottesville, VA, USA. sw3ta@virginia.edu.; Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA. sw3ta@virginia.edu., Lai ZM; Department of Anesthesiology, Fujian Medical University Union Hospital, 29 Xin-Quan Road, Fuzhou, Fujian, 350001, China. zl7mg@fjmu.edu.cn. |
| Source: | Molecular psychiatry [Mol Psychiatry] 2025 Nov; Vol. 30 (11), pp. 5192-5202. Date of Electronic Publication: 2025 Jul 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
