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Signatures of selection and mechanisms of insecticide resistance in Ugandan Anopheles funestus: Insights from embedding translational genomics into the LLINEUP cluster randomised trial.

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Title: Signatures of selection and mechanisms of insecticide resistance in Ugandan Anopheles funestus: Insights from embedding translational genomics into the LLINEUP cluster randomised trial.
Authors: Namuli-Kayondo L; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK and Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda and National Malaria Elimination Division, Ministry of Health, Kampala, Uganda., Nagi SC; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK., Nganga HN; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK., Hernandez-Koutoucheva A; Wellcome Sanger Institute, Hinxton, United Kingdom., McDermott DP; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK., Gonahasa S; Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda. and Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK., Lynd A; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK., Oruni A; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK., Maiteki-Sebuguzi C; National Malaria Elimination Division, Ministry of Health, Kampala, Uganda., Opigo J; National Malaria Elimination Division, Ministry of Health, Kampala, Uganda., Yeka A; Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda., Katureebe A; Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda., Kyohere M; Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda., Kamya MR; Makerere University College of Health Sciences. Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda., Dorsey G; University of California, San Francisco, San Francisco, CA 94110 USA., Hemingway J; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK., Staedke SG; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK., Nsobya SL; Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda., Nankabirwa JI; Makerere University College of Health Sciences. Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda., Kayondo J; Uganda Virus Research Institute, Entebbe, Uganda., Clarkson C; Wellcome Sanger Institute, Hinxton, United Kingdom., Miles A; Wellcome Sanger Institute, Hinxton, United Kingdom., Lawniczak MKN; Wellcome Sanger Institute, Hinxton, United Kingdom., Lucas ER; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK., Donnelly MJ; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jun 19. Date of Electronic Publication: 2025 Jun 19.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Signatures of selection and mechanisms of insecticide resistance in Ugandan Anopheles funestus: Insights from embedding translational genomics into the LLINEUP cluster randomised trial.
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  Data: <searchLink fieldCode="AU" term="%22Namuli-Kayondo+L%22">Namuli-Kayondo L</searchLink>; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK and Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda and National Malaria Elimination Division, Ministry of Health, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Nagi+SC%22">Nagi SC</searchLink>; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Nganga+HN%22">Nganga HN</searchLink>; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Hernandez-Koutoucheva+A%22">Hernandez-Koutoucheva A</searchLink>; Wellcome Sanger Institute, Hinxton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McDermott+DP%22">McDermott DP</searchLink>; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Gonahasa+S%22">Gonahasa S</searchLink>; Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda. and Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Lynd+A%22">Lynd A</searchLink>; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Oruni+A%22">Oruni A</searchLink>; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Maiteki-Sebuguzi+C%22">Maiteki-Sebuguzi C</searchLink>; National Malaria Elimination Division, Ministry of Health, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Opigo+J%22">Opigo J</searchLink>; National Malaria Elimination Division, Ministry of Health, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Yeka+A%22">Yeka A</searchLink>; Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Katureebe+A%22">Katureebe A</searchLink>; Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Kyohere+M%22">Kyohere M</searchLink>; Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Kamya+MR%22">Kamya MR</searchLink>; Makerere University College of Health Sciences. Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Dorsey+G%22">Dorsey G</searchLink>; University of California, San Francisco, San Francisco, CA 94110 USA.<br /><searchLink fieldCode="AU" term="%22Hemingway+J%22">Hemingway J</searchLink>; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Staedke+SG%22">Staedke SG</searchLink>; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Nsobya+SL%22">Nsobya SL</searchLink>; Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Nankabirwa+JI%22">Nankabirwa JI</searchLink>; Makerere University College of Health Sciences. Infectious Diseases Research Collaboration, 2C Nakasero Hill Road, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Kayondo+J%22">Kayondo J</searchLink>; Uganda Virus Research Institute, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Clarkson+C%22">Clarkson C</searchLink>; Wellcome Sanger Institute, Hinxton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Miles+A%22">Miles A</searchLink>; Wellcome Sanger Institute, Hinxton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lawniczak+MKN%22">Lawniczak MKN</searchLink>; Wellcome Sanger Institute, Hinxton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lucas+ER%22">Lucas ER</searchLink>; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Donnelly+MJ%22">Donnelly MJ</searchLink>; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
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