Reversal of MPPa-PDT Resistance in Osteosarcoma by Targeting ROCK2-Mediated Autophagy.

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Title: Reversal of MPPa-PDT Resistance in Osteosarcoma by Targeting ROCK2-Mediated Autophagy.
Authors: Yi X; Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Institute of Orthopedics of Jiangxi Province, Nanchang, China.; Jiangxi Provincial Key Laboratory of Spine and Spinal Cord Disease, Nanchang, China.; Institute of Minimally Invasive Orthopedics, Nanchang University, Nanchang, China., Deng X; Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Department of Rehabilitation, The Second Affiliated Hospital of Nanchang University, Nanchang, China., Deng J; Department of Vascular & Interventional & Lymphatic Surgery, The First Hospital of Nanchang, Nanchang, China., Li C; Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Institute of Orthopedics of Jiangxi Province, Nanchang, China.; Jiangxi Provincial Key Laboratory of Spine and Spinal Cord Disease, Nanchang, China.; Institute of Minimally Invasive Orthopedics, Nanchang University, Nanchang, China., Peng H; Department of Anorectal Surgery, Changcheng Hospital Affiliated to Nanchang University, Nanchang, China.; Department of Anorectal Surgery, No 908th Hospital of Chinese, Nanchang, China., Du Y; Department of Pharmacology, School of Pharmaceutical Science, Nanchang University, Nanchang, China., Li Q; Department of Pathology, The Second Affiliated Hospital of Nanchang University, Nanchang, China., Yan X; The MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China., Hu X; Department of Orthopedics, Pingxiang People's Hospital, PingXiang, China., Zheng Y; Department of Medical Genetics, The Second Affiliated Hospital of Nanchang University, Nanchang, China., Chen S; Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Institute of Orthopedics of Jiangxi Province, Nanchang, China.; Jiangxi Provincial Key Laboratory of Spine and Spinal Cord Disease, Nanchang, China.; Institute of Minimally Invasive Orthopedics, Nanchang University, Nanchang, China., Xiong T; Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Institute of Orthopedics of Jiangxi Province, Nanchang, China.; Jiangxi Provincial Key Laboratory of Spine and Spinal Cord Disease, Nanchang, China.; Institute of Minimally Invasive Orthopedics, Nanchang University, Nanchang, China., Xu D; Department of General Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China., Chen L; Department of Oncology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Medical Center for Cardiovascular Diseases, Neurological Diseases and Tumors of Jiangxi Province, The Second Affiliated Hospital of Nanchang University, Nanchang, China., Hao L; Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Institute of Orthopedics of Jiangxi Province, Nanchang, China.; Jiangxi Provincial Key Laboratory of Spine and Spinal Cord Disease, Nanchang, China.; Institute of Minimally Invasive Orthopedics, Nanchang University, Nanchang, China.
Source: Cell proliferation [Cell Prolif] 2026 Apr; Vol. 59 (4), pp. e70097. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article
Journal Info: Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications Country of Publication: England NLM ID: 9105195 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2184 (Electronic) Linking ISSN: 09607722 NLM ISO Abbreviation: Cell Prolif Subsets: MEDLINE
Database: MEDLINE Ultimate
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