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Whole genome DNA methylation patterns in tissue and cfDNA associated with fibrosis reflect the complex signature of MASLD.

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Title: Whole genome DNA methylation patterns in tissue and cfDNA associated with fibrosis reflect the complex signature of MASLD.
Authors: Ahn J; IMBdx, Seoul, Republic of Korea., Kim S; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Jeong JY; Department of Internal Medicine, Ewha Womans University College of Medicine, Division of Gastroenterology and Hepatology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea., Heo S; IMBdx, Seoul, Republic of Korea., Pyo KH; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Shin EA; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Kim W; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Lee JH; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Choi NR; Department of Internal Medicine, Ewha Womans University College of Medicine, Division of Gastroenterology and Hepatology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea., Lee HA; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea., Kim HP; IMBdx, Seoul, Republic of Korea., Song SH; IMBdx, Seoul, Republic of Korea., Kim HY; Department of Internal Medicine, Ewha Womans University College of Medicine, Division of Gastroenterology and Hepatology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea., Kim TY; IMBdx, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Lee JW; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.
Source: PloS one [PLoS One] 2025 Jul 17; Vol. 20 (7), pp. e0328207. Date of Electronic Publication: 2025 Jul 17 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
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  Data: Whole genome DNA methylation patterns in tissue and cfDNA associated with fibrosis reflect the complex signature of MASLD.
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  Data: <searchLink fieldCode="AU" term="%22Ahn+J%22">Ahn J</searchLink>; IMBdx, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+JY%22">Jeong JY</searchLink>; Department of Internal Medicine, Ewha Womans University College of Medicine, Division of Gastroenterology and Hepatology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Heo+S%22">Heo S</searchLink>; IMBdx, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Pyo+KH%22">Pyo KH</searchLink>; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+EA%22">Shin EA</searchLink>; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+W%22">Kim W</searchLink>; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+NR%22">Choi NR</searchLink>; Department of Internal Medicine, Ewha Womans University College of Medicine, Division of Gastroenterology and Hepatology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HA%22">Lee HA</searchLink>; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HP%22">Kim HP</searchLink>; IMBdx, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Song+SH%22">Song SH</searchLink>; IMBdx, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HY%22">Kim HY</searchLink>; Department of Internal Medicine, Ewha Womans University College of Medicine, Division of Gastroenterology and Hepatology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+TY%22">Kim TY</searchLink>; IMBdx, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JW%22">Lee JW</searchLink>; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.
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